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Share Tracking Awards Plans - Expense Recognized (Details) - Share tracking award plans (STAP) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Share based compensation benefit recognized in connection with the STAP    
Share-based compensation benefit before taxes $ (24.6) $ (147.9)
Related income tax expense 9.0 52.4
Share-based compensation benefit, net of taxes (15.6) (95.5)
Cash payments on awards exercised during the period 32.4 13.8
Cost of product sales    
Share based compensation benefit recognized in connection with the STAP    
Share-based compensation benefit before taxes (1.7) (12.0)
Research and development    
Share based compensation benefit recognized in connection with the STAP    
Share-based compensation benefit before taxes (5.8) (37.4)
Selling, general and administrative    
Share based compensation benefit recognized in connection with the STAP    
Share-based compensation benefit before taxes $ (17.1) $ (98.5)