Share Tracking Awards Plans (Details 2) - Share tracking award plans (STAP) - USD ($) $ in Millions	3 Months Ended
Mar. 31, 2016	Mar. 31, 2015
Share-based compensation (benefit) expense recognized in connection with the STAP
Share-based compensation expense before taxes		$ 234.2
Share-based compensation (benefit) before taxes	$ (147.9)
Related income tax benefit		(89.2)
Related income tax (benefit)	52.4
Share-based compensation expense, net of taxes		145.0
Share-based compensation (benefit) net of taxes	(95.5)
Share-based compensation expense capitalized as part of inventory	0.7	2.3
Cash payments on awards exercised during the period	13.8	98.5
Cost of product sales
Share-based compensation (benefit) expense recognized in connection with the STAP
Share-based compensation expense before taxes		9.6
Share-based compensation (benefit) before taxes	(12.0)
Research and development
Share-based compensation (benefit) expense recognized in connection with the STAP
Share-based compensation expense before taxes		74.9
Share-based compensation (benefit) before taxes	(37.4)
Selling, general and administrative
Share-based compensation (benefit) expense recognized in connection with the STAP
Share-based compensation expense before taxes		$ 149.7
Share-based compensation (benefit) before taxes	$ (98.5)

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SAB TOPIC 14.F)
-URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)(i)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

Reference 4: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Staff Accounting Bulletin (SAB)
-Number Topic 14
-Section F

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The amount of expense, net of income tax, recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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Aggregate cash paid by the entity during the period to settle equity instruments granted under equity-based payment arrangements.

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The total recognized tax benefit related to compensation cost for equity-based payment arrangements recognized in income during the period.

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Represents the expense reversed during the period arising from adjustments to equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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