CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Sep. 30, 2014	Sep. 30, 2013
Revenues:
Net product sales	$ 328,269	$ 300,006	$ 934,152	$ 820,647
Other	1,681	2,219	8,004	7,320
Total revenues	329,950	302,225	942,156	827,967
Operating expenses:
Research and development	118,876	72,749	171,067	177,796
Selling, general and administrative	202,507	94,111	300,753	236,832
Cost of product sales	40,803	30,716	110,113	92,349
Total operating expenses	362,186	197,576	581,933	506,977
Operating income	(32,236)	104,649	360,223	320,990
Other (expense) income:
Interest expense	(4,709)	(4,540)	(14,065)	(13,496)
Other, net	1,112	1,070	4,258	3,039
Total other expense, net	(3,597)	(3,470)	(9,807)	(10,457)
(Loss) income from continuing operations before income taxes	(35,833)	101,179	350,416	310,533
Income tax benefit (expense)	10,596	(38,494)	(126,277)	(105,659)
Net (loss) income	$ (25,237)	$ 62,685	$ 224,139	$ 204,874
Net (loss) income per common share:
Basic (in dollars per share)	$ (0.53)	$ 1.25	$ 4.63	$ 4.10
Diluted (in dollars per share)	$ (0.53)	$ 1.17	$ 4.12	$ 3.90
Weighted average number of common shares outstanding:
Basic (in shares)	47,297	50,014	48,427	50,007
Diluted (in shares)	47,297	53,688	54,360	52,570