CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data	3 Months Ended		9 Months Ended
	Sep. 30, 2011	Sep. 30, 2010	Sep. 30, 2011	Sep. 30, 2010
Revenues:
Net product sales	$ 201,020	$ 168,236	$ 546,784	$ 428,306
Other	722	339	1,221	903
Total revenues	201,742	168,575	548,005	429,209
Operating expenses:
Research and development	59,433	40,337	131,379	103,391
Selling, general and administrative	16,656	45,593	98,775	120,699
Cost of product sales	22,676	20,155	63,577	49,139
Total operating expenses	98,765	106,085	293,731	273,229
Operating income	102,977	62,490	254,274	155,980
Other (expense) income:
Interest income	1,016	564	2,520	2,308
Interest expense	(5,416)	(4,809)	(16,256)	(14,255)
Equity loss in affiliate	(43)	(39)	(110)	(130)
Other, net	(278)	137	(1,301)	457
Total other (expense) income, net	(4,721)	(4,147)	(15,147)	(11,620)
Income from continuing operations before income taxes	98,256	58,343	239,127	144,360
Income tax expense	(17,641)	(18,217)	(65,073)	(47,332)
Income from continuing operations	80,615	40,126	174,054	97,028
Discontinued operations:
(Loss) income from discontinued operations, net of tax		(390)	7	(656)
Gain on disposal of discontinued operations, net of tax	3,783		618
Income (loss) from discontinued operations	3,783	(390)	625	(656)
Net income	$ 84,398	$ 39,736	$ 174,679	$ 96,372
Basic
Continuing operations (in dollars per share)	$ 1.38	$ 0.71	$ 3.00	$ 1.74
Discontinued operations (in dollars per share)	$ 0.07	$ (0.01)	$ 0.01	$ (0.01)
Net income per basic common share (in dollars per share)	$ 1.45	$ 0.70	$ 3.01	$ 1.73
Diluted
Continuing operations (in dollars per share)	$ 1.32	$ 0.67	$ 2.80	$ 1.63
Discontinued operations (in dollars per share)	$ 0.06	$ (0.01)	$ 0.01	$ (0.01)
Net income per diluted common share (in dollars per share)	$ 1.38	$ 0.66	$ 2.81	$ 1.62
Weighted average number of common shares outstanding:
Basic (in shares)	58,321	56,536	58,087	55,790
Diluted (in shares)	61,210	60,216	62,062	59,545