XML 52 R37.htm IDEA: XBRL DOCUMENT v3.22.0.1
Segment Information (Tables)
 12 Months Ended
Dec. 31, 2021
Segment Reporting [Abstract]  
Schedule of net product sales, cost of product sales and gross profit for each commercial product
Net product sales, cost of product sales, and gross profit for each of our commercial products were as follows (in millions):
Year Ended December 31, 2021
Tyvaso(1)
Remodulin(1)
OrenitramUnituxinAdcircaTotal
Net product sales$607.5 $513.7 $306.1 $202.3 $55.9 $1,685.5 
Cost of product sales26.8 37.9 19.7 14.2 23.9 122.5 
Gross profit$580.7 $475.8 $286.4 $188.1 $32.0 $1,563.0 
Year Ended December 31, 2020
Net product sales$483.3 $516.7 $293.1 $122.9 $67.3 $1,483.3 
Cost of product sales24.5 23.2 18.7 12.6 29.1 108.1 
Gross profit$458.8 $493.5 $274.4 $110.3 $38.2 $1,375.2 


Year Ended December 31, 2019
Net product sales$415.6 $587.0 $225.3 $113.7 $107.2 $1,448.8 
Cost of product sales19.6 21.1 15.0 15.7 46.2 117.6 
Gross profit$396.0 $565.9 $210.3 $98.0 $61.0 $1,331.2 
(1)Net product sales and cost of product sales include sales of delivery devices for the respective product, including, with respect to Remodulin, the Remunity Pump.
Schedule of net revenues from external customers by geographic area
Geographic revenues are determined based on the country in which our customers (distributors) are located. Total revenues from external customers by geographic area are as follows (in millions):
Year Ended December 31,202120202019
United States$1,564.2 $1,412.1 $1,323.2 
Rest-of-World121.3 71.2 125.6 
Total$1,685.5 $1,483.3 $1,448.8 
Schedule of concentration of risk disclosure
We recorded revenue from three distributors in the United States that exceeded ten percent of total revenues. Revenue from these three distributors as a percentage of total revenues is as follows:
Year Ended December 31,202120202019
Distributor 150 %55 %54 %
Distributor 229 %28 %22 %
Distributor 311 %8 %8 %
Schedule of long-lived assets (property, plant and equipment) located by geographic area
Long-lived assets (property, plant, and equipment) located by geographic area are as follows (in millions):
Year Ended December 31,202120202019
United States$768.1 $717.3 $723.1 
Rest-of-World12.8 14.3 15.4 
Total$780.9 $731.6 $738.5