Stockholders' Equity (Details 3) - USD ($) $ in Thousands	3 Months Ended					12 Months Ended
	Dec. 31, 2015	Jun. 30, 2015	Mar. 31, 2015	Dec. 31, 2014	Sep. 30, 2014	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Share-based compensation expense related to outstanding awards
Share-based compensation expense, net of taxes	$ 71,600	$ 27,500	$ 145,700	$ 19,900	$ 122,100
Unrecognized compensation cost related to employee stock options	$ 5,400			$ 0		$ 5,400	$ 0
Summary of stock option exercise data
Number of options exercised (in shares)						985,583	1,462,369	876,115
Cash received from options exercised						$ 39,311	$ 50,168	$ 26,619
Total intrinsic value of options exercised						120,319	108,425	37,530
Tax benefits realized from options exercised						37,426	30,845	9,299
Common stock issued in connection with ESPP, Amount						3,954	3,330	2,735
Share-based compensation expense						280,254	190,054	320,786
Stock Options
Share-based compensation expense related to outstanding awards
Related income tax benefit						(1,847)	(10,429)	(13,566)
Share-based compensation expense, net of taxes						$ 3,050	19,031	22,531
Summary of stock option exercise data
Number of options exercised (in shares)						984,583
Employee Stock Purchase Plan (ESPP)
Summary of stock option exercise data
Offering period						6 months
Maximum percentage of compensation employees may contribute for ESPP	15.00%					15.00%
Percentage of the lower of the fair market value of common stock on the first or last trading-day of a given offering period						85.00%
Maximum number of shares each eligible employees may purchase in any given offering period						4,000
Term of employee stock purchase plan						20 years
Maximum number of shares authorized to be issued	3,000,000					3,000,000
Research and development
Share-based compensation expense related to outstanding awards
Share-based compensation expense before taxes						$ 3
Selling, general and administrative | Stock Options
Share-based compensation expense related to outstanding awards
Share-based compensation expense before taxes						$ 4,894	$ 29,460	$ 36,097