Commitments and Contingencies (Tables)

12 Months Ended

Dec. 31, 2015

Commitments and Contingencies.

Schedule of future minimum lease payments under non-cancelable operating leases

        Future minimum lease payments under non-cancelable operating leases as of December 31, 2015 are as follows (in thousands):

Year Ending December 31,
2016	$	3,716
2017		3,447
2018		2,636
2019		498
2020		237
Thereafter		—
Total	$	10,534

Future milestone payments under assignment and license agreements

        Future milestone payments based on our estimates of the timing and probability of achieving milestones specified under these arrangements are as follows (in thousands):

Year Ending December 31,	(1)
2016	$	6,136
2017		4,640
2018		3,705
2019		9,711
2020		1,759
Thereafter		7,070
Total	$	33,021

(1)           The amounts and timing of future milestone payments may vary depending on when related milestones will be attained, if at all.