Segment Information

12 Months Ended

Dec. 31, 2013

Segment Information

Segment Information

19. Segment Information

        Prior to June 2011, we operated in two business segments: pharmaceutical and telemedicine. Following the sale of our telemedicine subsidiary, Medicomp, and the discontinuation of further telemedicine-related activities in 2011, we began managing our business as one operating segment. However, our chief operating decision makers regularly review revenues, cost of revenues and gross profit data as a primary measure of performance for each of our three commercial products. Note that we expect to commence sales of our most recently approved commercial product, Orenitram, in mid-2014.

        Revenues, cost of revenues and gross profit for each of our commercial products are as follows (in thousands):

	Remodulin		Tyvaso		Adcirca		Total
Year Ended December 31, 2013
Revenues	$	491,179	$	438,793	$	176,972	$	1,106,944
Cost of revenues		59,314		60,831		10,982		131,127
Gross profit	$	431,865	$	377,962	$	165,990	$	975,817
Year Ended December 31, 2012
Revenues	$	457,969	$	325,614	$	122,540	$	906,123
Cost of revenues		57,618		53,825		7,854		119,297
Gross profit	$	400,351	$	271,789	$	114,686	$	786,826
Year Ended December 31, 2011
Revenues	$	430,132	$	240,382	$	70,580	$	741,094
Cost of revenues		52,329		31,934		4,641	$	88,904
Gross profit	$	377,803	$	208,448	$	65,939	$	652,190

        Geographic revenues are determined based on the country in which our customers (distributors) are located. Net revenues from external customers by geographic area are as follows (in thousands):

Year Ended December 31,	2013		2012		2011
United States	$	1,032,435	$	846,611	$	676,967
Rest-of-World(1)		84,549		69,465		66,216
Total	$	1,116,984	$	916,076	$	743,183

(1)

Primarily Europe.

        For the years ended December 31, 2013, 2012 and 2011, sales to Accredo Health Group, Inc. comprised 57 percent, 56 percent and 61 percent, respectively, of total consolidated net revenues.

        Long-lived assets (property, plant and equipment) located by geographic area are as follows (in thousands):

Year Ended December 31,	2013		2012		2011
United States	$	442,673	$	425,585	$	345,153
Rest-of-World(1)		22,277		28,100		20,893
Total	$	464,950	$	453,685	$	366,046

(1)

Facilities principally located in the United Kingdom.