Exhibit 12.1

COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES

The following table sets forth our ratio of earnings to fixed charges for each of the periods indicated (in thousands):

	Year Ended December 31,
	2004			2003			2002			2001			2000
Earnings:
Net loss	$	(27,637	)	$	(22,698	)	$	(37,173	)	$	(44,928	)	$	(19,851	)
Fixed charges		5,661			3,584			1,391			1,125			1,366
Less: Interest Capitalized		—			—			—			—			—
Total Earnings:	$	(21,976	)	$	(19,114	)	$	(35,782	)	$	(43,803	)	$	(18,485	)
Fixed Charges:
Interest expense		4,463			2,460			280			322			131
Portion of rent expense representative of interest		1,198			1,124			1,111			803			263
Preferred stock dividends		—			—			—			—			972
Total Fixed Charges	$	5,661		$	3,584		$	1,391		$	1,125		$	1,366
Ratio of earnings to fixed charges (1)		—			—			—			—			—

(1) For purposes of computing the ratio of earnings to fixed charges, earnings consist of net loss plus fixed charges. Fixed charges consist of interest expense, amortization of debt expense and discount or premium related to indebtedness, whether expensed or capitalized, and that portion of rental payments under operating leases we believe to be representative of interest. Earnings were insufficient to cover fixed charges for these periods. The amount of the coverage deficiency was $18,485, $43,803, $35,782, $19,114 and $21,976 for the years ended December 31, 2000, 2001, 2002, 2003 and 2004, respectively.