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Financial Instruments and Fair Value Measurements - Equity Investment in Entasis (Details) - Entasis
$ / shares in Units, $ in Millions
3 Months Ended
Mar. 31, 2021
USD ($)
director
Sep. 30, 2020
USD ($)
$ / shares
shares
Jun. 30, 2020
USD ($)
$ / shares
shares
Dec. 31, 2020
USD ($)
Equity Investment        
Number of investee's board members which may be designated by the Company | director 2      
Number of Investee's Board members currently representing the Company | director 0      
Number of the Investee's Board members | director 6      
Equity investment ownership percentage 51.00%      
Unrealized loss from fair value changes in equity investments $ (11.5)      
Common stock and warrants        
Equity Investment        
Payments to acquire equity securities   $ 12.5 $ 35.0  
Fair value of equity securities 66.6     $ 78.0
Common stock        
Equity Investment        
Number of shares purchased under the securities purchase agreement | shares   4,672,897 14,000,000  
Fair value of equity securities 40.0     46.1
Warrants        
Equity Investment        
Number of warrants purchased under the securities purchase agreement | shares   4,672,897 14,000,000  
Fair value of equity securities $ 26.6     $ 31.9
Warrants acquired in second quarter of 2020        
Equity Investment        
Exercise price of warrants | $ / shares     $ 2.50  
Term of warrants     5 years  
Warrants acquired in third quarter of 2020        
Equity Investment        
Exercise price of warrants | $ / shares   $ 2.675    
Term of warrants   5 years