Financial Instruments and Fair Value Measurements - Fair Value Measurements (Details) - USD ($) $ in Thousands	Jun. 30, 2020	Dec. 31, 2019
Recurring basis
Assets
Total assets measured at estimated fair value	$ 511,084	$ 306,741
Recurring basis | U.S. government securities
Assets
Total assets measured at estimated fair value	3,999	53,834
Recurring basis | U.S. commercial paper
Assets
Total assets measured at estimated fair value		18,915
Recurring basis | Money market funds
Assets
Total assets measured at estimated fair value	378,472	233,992
Recurring basis | Equity Investment | Common stock | Armata
Assets
Total assets measured at estimated fair value	34,146
Recurring basis | Equity Investment | Common stock | Entasis
Assets
Total assets measured at estimated fair value	41,440
Recurring basis | Equity Investment | Warrants | Armata
Assets
Total assets measured at estimated fair value	26,181
Recurring basis | Equity Investment | Warrants | Entasis
Assets
Total assets measured at estimated fair value	26,846
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1
Assets
Total assets measured at estimated fair value	454,058	233,992
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | U.S. government securities
Assets
Total assets measured at estimated fair value	0	0
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | U.S. commercial paper
Assets
Total assets measured at estimated fair value		0
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Money market funds
Assets
Total assets measured at estimated fair value	378,472	233,992
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity Investment | Common stock | Armata
Assets
Total assets measured at estimated fair value	34,146
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity Investment | Common stock | Entasis
Assets
Total assets measured at estimated fair value	41,440
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity Investment | Warrants | Armata
Assets
Total assets measured at estimated fair value	0
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity Investment | Warrants | Entasis
Assets
Total assets measured at estimated fair value	0
Recurring basis | Significant Other Observable Inputs, Level 2
Assets
Total assets measured at estimated fair value	57,026	72,749
Recurring basis | Significant Other Observable Inputs, Level 2 | U.S. government securities
Assets
Total assets measured at estimated fair value	3,999	53,834
Recurring basis | Significant Other Observable Inputs, Level 2 | U.S. commercial paper
Assets
Total assets measured at estimated fair value		18,915
Recurring basis | Significant Other Observable Inputs, Level 2 | Money market funds
Assets
Total assets measured at estimated fair value	0	0
Recurring basis | Significant Other Observable Inputs, Level 2 | Equity Investment | Common stock | Armata
Assets
Total assets measured at estimated fair value	0
Recurring basis | Significant Other Observable Inputs, Level 2 | Equity Investment | Common stock | Entasis
Assets
Total assets measured at estimated fair value	0
Recurring basis | Significant Other Observable Inputs, Level 2 | Equity Investment | Warrants | Armata
Assets
Total assets measured at estimated fair value	26,181
Recurring basis | Significant Other Observable Inputs, Level 2 | Equity Investment | Warrants | Entasis
Assets
Total assets measured at estimated fair value	26,846
Recurring basis | Significant Unobservable Inputs, Level 3
Assets
Total assets measured at estimated fair value	0	0
Recurring basis | Significant Unobservable Inputs, Level 3 | U.S. government securities
Assets
Total assets measured at estimated fair value	0	0
Recurring basis | Significant Unobservable Inputs, Level 3 | U.S. commercial paper
Assets
Total assets measured at estimated fair value		0
Recurring basis | Significant Unobservable Inputs, Level 3 | Money market funds
Assets
Total assets measured at estimated fair value	0	0
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity Investment | Common stock | Armata
Assets
Total assets measured at estimated fair value	0
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity Investment | Common stock | Entasis
Assets
Total assets measured at estimated fair value	0
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity Investment | Warrants | Armata
Assets
Total assets measured at estimated fair value	0
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity Investment | Warrants | Entasis
Assets
Total assets measured at estimated fair value	0
Nonrecurring basis | Debt
Debt
2023 Notes	246,303	243,394
2025 Notes	198,997	208,976
Total fair value of debt	445,300	452,370
Nonrecurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Debt
Debt
2023 Notes	0	0
2025 Notes	0	0
Total fair value of debt	0	0
Nonrecurring basis | Significant Other Observable Inputs, Level 2 | Debt
Debt
2023 Notes	246,303	243,394
2025 Notes	198,997	208,976
Total fair value of debt	445,300	452,370
Nonrecurring basis | Significant Unobservable Inputs, Level 3 | Debt
Debt
2023 Notes	0	0
2025 Notes	0	0
Total fair value of debt	$ 0	$ 0