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Financial Instruments and Fair Value Measurements - Equity Investment in Entasis (Details)
$ / shares in Units, $ in Thousands
3 Months Ended 6 Months Ended
Apr. 12, 2020
USD ($)
$ / shares
shares
Jun. 30, 2020
USD ($)
Jun. 30, 2019
USD ($)
Jun. 30, 2020
USD ($)
item
tranche
Jun. 30, 2019
USD ($)
Equity Investment          
Changes in fair values of equity investments   $ 46,698 $ 0 $ 68,613 $ 0
Entasis          
Equity Investment          
Number of tranches | tranche       2  
Number of investee's board members which may be designated by the Company | item       2  
Equity investment ownership percentage 51.30%        
Changes in fair values of equity investments   33,300   $ 33,300  
Common stock and warrants | Entasis          
Equity Investment          
Amount of securities purchase agreement $ 35,000        
Equity investments at fair value   68,300   68,300  
Common stock | Entasis          
Equity Investment          
Number of shares to be purchased under the securities purchase agreement | shares 14,000,000        
Equity investments at fair value   41,400   41,400  
Warrants | Entasis          
Equity Investment          
Maximum number of additional shares into which warrants may be converted under the securities purchase agreement | shares 14,000,000        
Exercise price of warrants | $ / shares $ 2.50        
Term of warrants 5 years        
Equity investments at fair value   $ 26,900   $ 26,900