Revenue Recognition and Collaborative Arrangements (Details) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Revenue Recognition and Collaborative Arrangements
Total net revenue from GSK	$ 61,680	$ 48,643	$ 181,146	$ 147,697
Royalty revenue from a related party
Revenue Recognition and Collaborative Arrangements
Less: amortization of capitalized fees paid to a related party	(3,456)	(3,456)	(10,368)	(10,368)
Total net revenue from GSK	61,680	48,422	181,146	147,034
Revenue from collaborative arrangements from a related party
Revenue Recognition and Collaborative Arrangements
Total net revenue from GSK	0	221	0	663
GSK
Revenue Recognition and Collaborative Arrangements
Total net revenue from GSK	61,680	48,643	181,146	147,697
GSK \| Royalty revenue from a related party
Revenue Recognition and Collaborative Arrangements
Royalties from a related party	65,136	51,878	191,514	157,402
Less: amortization of capitalized fees paid to a related party	(3,456)	(3,456)	(10,368)	(10,368)
Total net revenue from GSK	61,680	48,422	181,146	147,034
GSK \| RELVAR/BREO
Revenue Recognition and Collaborative Arrangements
Royalties from a related party	51,745	44,604	155,420	137,938
GSK \| ANORO
Revenue Recognition and Collaborative Arrangements
Royalties from a related party	9,769	7,274	29,149	19,464
GSK \| TRELEGY
Revenue Recognition and Collaborative Arrangements
Royalties from a related party	3,622	0	6,945	0
Strategic alliance - MABA program license \| GSK \| Revenue from collaborative arrangements from a related party
Revenue Recognition and Collaborative Arrangements
Total net revenue from GSK	$ 0	$ 221	$ 0	$ 663

Gross Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer before amortization of capitalized fees.

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Amount of amortization expense for asset recognized from cost incurred to obtain or fulfill contract with customer.

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
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-Topic 340
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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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-Name Accounting Standards Codification
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-URI http://asc.fasb.org/extlink&oid=109196051&loc=SL49130545-203045

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