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Discontinued Operations (Details) (USD $)
3 Months Ended 6 Months Ended 3 Months Ended 6 Months Ended 1 Months Ended 3 Months Ended 12 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Discontinued operations
Jun. 30, 2013
Discontinued operations
Jun. 30, 2014
Discontinued operations
Jun. 30, 2013
Discontinued operations
May 31, 2014
Discontinued operations
Special Long-Term Retention and Incentive Cash Awards Program
Mar. 31, 2014
Discontinued operations
Special Long-Term Retention and Incentive Cash Awards Program
Dec. 31, 2011
Discontinued operations
Special Long-Term Retention and Incentive Cash Awards Program
Components of research and drug development operations presented on condensed consolidated statements of operations                      
Net revenues $ 2,184,000 $ 5,000 $ 3,129,000 $ 27,000              
Loss from discontinued operations (43,413,000) (34,888,000) (94,934,000) (61,502,000)              
Reimbursement of research and development costs from discontinued operations from collaborative arrangements         22,000 2,100,000 100,000 3,900,000      
Timeframe for achievement of performance conditions                     6 years
Stock-based compensation expense 7,747,000 7,162,000 21,281,000 13,257,000 4,152,000 4,994,000 11,629,000 9,355,000      
Compensation expenses related to cash bonus recognized in current year given sufficient performance conditions achieved                   9,100,000  
Total cash bonus paid                 $ 9,500,000