CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2014	Mar. 31, 2013
Revenue:
Product sales	$ 945	$ 0
Royalty revenue from a related party, net of intangible assets amortization of $1,780 and $0 for the three months ended March 31, 2014 and 2013 (Note 3)	(1,050)	0
Net revenue from collaborative arrangements (including amounts from a related party of $270 and $1,322 for the three months ended March 31, 2014 and 2013)	270	1,344
Total net revenue	165	1,344
Costs and expenses:
Cost of goods sold	188	0
Research and development	43,387	26,416
Selling, general and administrative	22,834	8,315
Total costs and expenses	66,409	34,731
Loss from operations	(66,244)	(33,387)
Other income (expense), net	(3)	(1,422)
Interest income	188	185
Interest expense	(1,644)	(2,736)
Net loss	$ (67,703)	$ (37,360)
Basic and diluted net loss per share (in dollars per share)	$ (0.62)	$ (0.39)
Shares used to compute basic and diluted net loss share (in shares)	109,859	96,379