CONDENSED CONSOLIDATED BALANCE SHEETS (USD $) In Thousands	Sep. 30, 2011	Dec. 31, 2010
Current assets:
Cash and cash equivalents	$ 62,736	$ 163,333
Marketable securities	202,433	146,301
Accounts receivable from related party	63	194
Notes receivable	85	531
Prepaid expenses and other current assets	3,848	5,995
Total current assets	269,165	316,354
Restricted cash	893	893
Property and equipment, net	10,206	10,215
Notes receivable	340	400
Other assets	2,721	3,340
Total assets	283,325	331,202
Current liabilities:
Accounts payable	3,699	2,128
Accrued personnel-related expenses	7,123	8,617
Accrued clinical and development expenses	5,075	2,801
Accrued interest on convertible subordinated notes	1,078	2,372
Other current liabilities	1,843	2,008
Note payable and capital lease, current	109	206
Deferred revenue, current	20,887	21,922
Total current liabilities	39,814	40,054
Convertible subordinated notes	172,500	172,500
Deferred rent, non-current	5,728	3,574
Note payable and capital lease, non-current		69
Deferred revenue, non-current	124,435	137,425
Commitments and contingencies (Notes 4, 8 and 9)
Stockholders' net capital deficiency:
Additional paid-in capital	1,218,934	1,177,359
Accumulated other comprehensive income	16	33
Accumulated deficit	(1,278,953)	(1,200,616)
Total stockholders' net capital deficiency	(59,152)	(22,420)
Total liabilities and stockholders' net capital deficiency	283,325	331,202
Common stock
Stockholders' net capital deficiency:
Common stock	851	710
Class A common stock
Stockholders' net capital deficiency:
Common stock		$ 94