CONDENSED CONSOLIDATED BALANCE SHEETS (USD $) In Thousands	Jun. 30, 2011	Dec. 31, 2010
Current assets:
Cash and cash equivalents	$ 90,658	$ 163,333
Marketable securities	193,229	146,301
Accounts receivable from related party	32	194
Notes receivable	200	531
Prepaid expenses and other current assets	4,506	5,995
Total current assets	288,625	316,354
Restricted cash	893	893
Property and equipment, net	10,334	10,215
Notes receivable	340	400
Other assets	2,928	3,340
Total assets	303,120	331,202
Current liabilities:
Accounts payable	2,165	2,128
Accrued personnel-related expenses	5,154	8,617
Accrued clinical and development expenses	2,850	2,801
Accrued interest on convertible subordinated notes	2,372	2,372
Other current liabilities	1,935	2,008
Note payable and capital lease, current	162	206
Deferred revenue, current	20,553	21,922
Total current liabilities	35,191	40,054
Convertible subordinated notes	172,500	172,500
Deferred rent, non-current	5,518	3,574
Note payable and capital lease, non-current		69
Deferred revenue	127,393	137,425
Commitments and contingencies (Notes 4, 8 and 9)
Stockholders' net capital deficiency:
Additional paid-in capital	1,210,006	1,177,359
Accumulated other comprehensive income (loss)	(8)	33
Accumulated deficit	(1,248,328)	(1,200,616)
Total stockholders' net capital deficiency	(37,482)	(22,420)
Total liabilities and stockholders' net capital deficiency	303,120	331,202
Common stock
Stockholders' net capital deficiency:
Common stock	754	710
Class A common stock
Stockholders' net capital deficiency:
Common stock	$ 94	$ 94