-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, EscgTrGgmj2K/9xZz7LryMWFG/0kTxLszjB+yAARF9zBrOQstm3xY7241m0H3wKh LRgddLuTxmv17ESJyHJqgg== 0001104659-08-002853.txt : 20080115 0001104659-08-002853.hdr.sgml : 20080115 20080115160557 ACCESSION NUMBER: 0001104659-08-002853 CONFORMED SUBMISSION TYPE: 8-K PUBLIC DOCUMENT COUNT: 3 CONFORMED PERIOD OF REPORT: 20080115 ITEM INFORMATION: Other Events ITEM INFORMATION: Financial Statements and Exhibits FILED AS OF DATE: 20080115 DATE AS OF CHANGE: 20080115 FILER: COMPANY DATA: COMPANY CONFORMED NAME: THERAVANCE INC CENTRAL INDEX KEY: 0001080014 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 943265960 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 8-K SEC ACT: 1934 Act SEC FILE NUMBER: 000-30319 FILM NUMBER: 08531339 BUSINESS ADDRESS: STREET 1: 901 GATEWAY BLVD CITY: SOUTH SAN FRANCISCO STATE: CA ZIP: 94080 BUSINESS PHONE: 6508086000 MAIL ADDRESS: STREET 1: 901 GATEWAY BLVD CITY: S. SAN FRANCISCO STATE: CA ZIP: 94080 FORMER COMPANY: FORMER CONFORMED NAME: ADVANCED MEDICINE INC DATE OF NAME CHANGE: 20000302 8-K 1 a08-2067_18k.htm 8-K

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC  20549

 


 

FORM 8-K

 


 

Current Report Pursuant

to Section 13 or 15(d) of the

Securities Exchange Act of 1934

 

Date of Report (Date of earliest event Reported):  January 15, 2008

 


 

THERAVANCE, INC.

(Exact Name of Registrant as Specified in its Charter)

 

Delaware

(State or Other Jurisdiction
of Incorporation)

 

000-30319

(Commission File Number)

 

94-3265960

(I.R.S. Employer
Identification Number)

 

901 Gateway Boulevard
South San Francisco, California 94080
(650) 808-6000

(Addresses, including zip code, and telephone numbers, including area code, of principal executive offices)

 


 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

 

o  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

o  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

o  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

o  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 

 

 



 

Item 8.01.  Other Events.

 

On January 3, 2008 Theravance, Inc. and GlaxoSmithKline Plc issued a joint press release with information regarding a recently-completed Phase 2 study of the lead inhaled corticosteroid (ICS) GW685698 (‘698) asset in the ‘Horizon’ program to develop a next-generation combination product involving an ICS and a long-acting beta agonist. In the Phase 2 study, ‘698 demonstrated once-a-day efficacy in patients with moderate asthma, with improvements in lung function in excess of 200mL.  Further information regarding the results of this Phase 2 study of ‘698 are summarized in the slide on Exhibit 99.1 to this report and incorporated herein by reference.

 

Item 9.01. Financial Statements and Exhibits

 

(d) Exhibits

 

99.1         Slide Regarding ‘698 ICS Phase 2 QD Dose-Ranging Study

 

2



 

SIGNATURE

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

 

 

 

 

THERAVANCE, INC.

 

 

 

 

 

 

Date: January 15, 2008

By:

/s/ Rick E Winningham

 

 

Rick E Winningham

 

 

Chief Executive Officer

 

 

 

 

3



 

Exhibit Index

 

Exhibit No.

 

Description

99.1

 

Slide Regarding ‘698 ICS Phase 2 QD Dose-Ranging Study

 

4


 

 

EX-99.1 2 a08-2067_1ex99d1.htm EX-99.1

Exhibit 99.1

 

GRAPHIC

® 1 ‘698 ICS Phase 2 QD Dose-Ranging Study Improved Lung Function vs. Placebo Mean change from baseline in trough FEV1 (L) following 8 weeks' treatment - 0.05 0.10 0.15 0.20 0.25 0.30 0.35 Placebo 200mcg QD 400mcg QD No adverse effect on cortisol excretion

 

 

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