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Discontinued Operations (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Jun. 30, 2013
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Components of research and drug development operations presented on the condensed consolidated statements of operations                
Net revenues           $ 0 $ 3,129 $ 226
Income (loss) from discontinued operations   $ 0 $ 0 $ (43,413) $ (51,521) $ 0 $ (94,934) $ (140,068)
Termination fee received recorded as discontinued operations $ 10,000