Property and Equipment

12 Months Ended

Dec. 31, 2012

6. Property and Equipment

Property and equipment consists of the following:

	December 31,

(in thousands)	2012			2011
Computer equipment	$	3,027		$	3,158
Software		5,073			4,628
Furniture and fixtures		3,829			3,821
Laboratory equipment		29,229			28,894
Leasehold improvements		17,416			17,263

		58,574			57,764
Less accumulated depreciation and amortization		(49,420	)		(47,392	)

Property and equipment, net	$	9,154		$	10,372

Depreciation expense was $3.3 million in 2012, $3.8 million in 2011 and $3.9 million in 2010. The change in accumulated depreciation is net of asset retirements. In 2012, the Company recognized a write-off of $0.2 million related to assets that could no longer be used in operations.

- Definition

The entire disclosure for long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale. Examples include land, buildings, machinery and equipment, and other types of furniture and equipment including, but not limited to, office equipment, furniture and fixtures, and computer equipment and software. This disclosure may include property plant and equipment accounting policies and methodology, a schedule of property, plant and equipment gross, additions, deletions, transfers and other changes, depreciation, depletion and amortization expense, net, accumulated depreciation, depletion and amortization expense and useful lives, income statement disclosures, assets held for sale and public utility disclosures.

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