Description of Operations and Summary of Significant Accounting Policies (Details) (USD $)	12 Months Ended
	Dec. 31, 2011 M	Dec. 31, 2010	Dec. 31, 2009
Cash, Cash Equivalents and Restricted Cash
Maximum term of original maturity to classify instruments as cash equivalents (in months)	3
Restricted cash	$ 893,000	$ 893,000
Information related to collaboration arrangements
Inventory sold at cost	24,512,000	24,223,000	24,374,000
License, Development and Commercialization Agreement With Astellas | VIBATIV
Information related to collaboration arrangements
Inventory sold at cost	1,171,000	2,058,000
Cost of unrealizable VIBATIV inventory	537,000	821,000	1,175,000
Astellas | License, Development and Commercialization Agreement With Astellas | VIBATIV
Information related to collaboration arrangements
Inventory sold at cost	1,171,000	2,058,000
Inventory of VIBATIV	$ 0	$ 1,700,000