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Property and Equipment (Tables)
12 Months Ended
Dec. 31, 2011
Property and Equipment  
Schedule of property and equipment
 
  December 31,  
(in thousands)
  2011   2010  

Computer equipment

  $ 3,158   $ 2,473  

Software

    4,628     4,592  

Furniture and fixtures

    3,821     3,689  

Laboratory equipment

    28,894     27,006  

Leasehold improvements

    17,263     16,101  
           

 

    57,764     53,861  

Less accumulated depreciation and amortization

    (47,392 )   (43,646 )
           

Property and equipment, net

  $ 10,372   $ 10,215