Property and Equipment

12 Months Ended

Dec. 31, 2011

6. Property and Equipment

Property and equipment consists of the following:

	December 31,

(in thousands)	2011			2010
Computer equipment	$	3,158		$	2,473
Software		4,628			4,592
Furniture and fixtures		3,821			3,689
Laboratory equipment		28,894			27,006
Leasehold improvements		17,263			16,101

		57,764			53,861
Less accumulated depreciation and amortization		(47,392	)		(43,646	)

Property and equipment, net	$	10,372		$	10,215

Depreciation expense was $3.8 million in 2011, $3.9 million in 2010 and $4.3 million in 2009. The change in accumulated depreciation is net of asset retirements.

- Definition

The entire disclosure for long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale. Examples include land, buildings, machinery and equipment, and other types of furniture and equipment including, but not limited to, office equipment, furniture and fixtures, and computer equipment and software. This disclosure may include property plant and equipment accounting policies and methodology, a schedule of property, plant and equipment gross, additions, deletions, transfers and other changes, depreciation, depletion and amortization expense, net, accumulated depreciation, depletion and amortization expense and useful lives, income statement disclosures, assets held for sale and public utility disclosures.

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