CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total	Common stock	Additional Paid-In Capital	Accumulated Deficit	Treasury Stock	Noncontrolling Interest	Cumulative Effect, Period of Adoption, Adjustment [Member]	Cumulative Effect, Period of Adoption, Adjustment [Member] Common stock	Cumulative Effect, Period of Adoption, Adjustment [Member] Additional Paid-In Capital	Cumulative Effect, Period of Adoption, Adjustment [Member] Accumulated Deficit	Cumulative Effect, Period of Adoption, Adjustment [Member] Treasury Stock	Cumulative Effect, Period of Adoption, Adjustment [Member] Noncontrolling Interest
Balance at Dec. 31, 2021	$ 525,935	$ 696	$ 1,264,024	$ (456,148)	$ (393,829)	$ 111,192
Balance (in shares) at Dec. 31, 2021		69,566,000			32,005,000
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Accounting Standards Update [Extensible Enumeration]			Accounting Standards Update 2020-06 [Member]	Accounting Standards Update 2020-06 [Member]			Accounting Standards Update 2020-06 [Member]
Distributions to noncontrolling interest	(6,507)	$ 0	$ 0	$ 0	$ 0	(6,507)
Distributions to noncontrolling interest (in shares)		0			0
Equity activity of noncontrolling interest from a consolidated variable interest entity	38,471	$ 0	0	0	$ 0	38,471
Equity activity of noncontrolling interest from a consolidated variable interest entity (in shares)		0			0
Issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding	214	$ 0	214	0	$ 0	0
Exercise of stock options and issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding		28,000			0
Stock-based compensation	954	$ 0	620	0	$ 0	334
Stock-based compensation (in shares)		0			0
Capped call options associated with convertible senior notes due 2028	(16,585)	$ 0	(16,585)	0	$ 0	0
Capped call options associated with convertible senior notes due 2028 (in shares)		0			0
Net income	37,858	$ 0	0	15,773	$ 0	22,085
Net Income (Shares)		0			0
Balance at Mar. 31, 2022	552,217	$ 696	1,182,912	(403,137)	$ (393,829)	165,575	$ (28,123)	$ 0	$ (65,361)	$ 37,238	$ 0	$ 0
Balance (in shares) at Mar. 31, 2022		69,594,000			32,005,000			0			0
Balance at Dec. 31, 2021	525,935	$ 696	1,264,024	(456,148)	$ (393,829)	111,192
Balance (in shares) at Dec. 31, 2021		69,566,000			32,005,000
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net income	288,576
Balance at Sep. 30, 2022	641,368	$ 698	1,171,096	(136,597)	$ (393,829)	0
Balance (in shares) at Sep. 30, 2022		69,776			32,005
Balance at Mar. 31, 2022	552,217	$ 696	1,182,912	(403,137)	$ (393,829)	165,575	$ (28,123)	$ 0	$ (65,361)	$ 37,238	$ 0	$ 0
Balance (in shares) at Mar. 31, 2022		69,594,000			32,005,000			0			0
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Distributions to noncontrolling interest	(9,545)	$ 0	0	0	$ 0	(9,545)
Distributions to noncontrolling interest (in shares)					0
Equity activity of noncontrolling interest from a consolidated variable interest entity	(2)	$ 0	0	0	$ 0	(2)
Equity activity of noncontrolling interest from a consolidated variable interest entity (in shares)		0			0
Issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding	68	$ 1	67	0	$ 0	0
Exercise of stock options and issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding		112,000			0
Conversion of convertible subordinated notes due 2023	3	$ 0	3	0	$ 0	0
Conversion of convertiblesubordinated notes due 2023 (in shares)		0			0
Stock-based compensation	1,350	$ 0	685	0	$ 0	665
Stock-based compensation (in shares)		0			0
Net income	21,371	$ 0	0	939	$ 0	20,432
Net Income (Shares)		0			0
Balance at Jun. 30, 2022	565,462	$ 697	1,183,667	(402,198)	$ (393,829)	177,125
Balance (in shares) at Jun. 30, 2022		69,706			32,005,000
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Distributions to noncontrolling interest	(53,759)	$ 0	0	0	$ 0	(53,759)
Distributions to noncontrolling interest (in shares)					0
Derecognition of noncontrolling interests upon sale of TRC	(61,226)	$ 0	0	78	$ 0	(61,304)
Derecognition of noncontrolling interests upon sale of TRC (in shares)		0			0
Derecognition of noncontrolling interests upon acquisition of Entasis Therapeutics Holdings Inc. ("Entasis") minority interest	(42,162)	$ 0	(14,153)	0	$ 0	(28,009)
Derecognition of noncontrolling interests upon acquisition of Entasis Therapeutics Holdings Inc ("Entasis") minority interest (in shares)		0			0
Issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding	(11)	$ 1	(12)	0	$ 0
Exercise of stock options and issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding		70			0
Stock-based compensation	3,717	$ 0	1,594	0	$ 0	2,123
Stock-based compensation (in shares)		0			0
Net income	229,347	$ 0	0	265,523	$ 0	(36,176)
Net Income (Shares)		0			0
Balance at Sep. 30, 2022	641,368	$ 698	1,171,096	(136,597)	$ (393,829)	$ 0
Balance (in shares) at Sep. 30, 2022		69,776			32,005
Balance at Jun. 30, 2023	555,087	$ 653	1,117,029	(168,766)	$ (393,829)
Balance (in shares) at Jun. 30, 2023		65,225,000			32,005,000
Balance at Dec. 31, 2022	$ 565,788	$ 692	1,163,836	(204,911)	$ (393,829)
Balance (in shares) at Dec. 31, 2022	69,188,000	69,188,000			32,005,000
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding	$ (23)	$ 1	(24)	0	$ 0
Exercise of stock options and issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding		55,000			0
Repurchase of common stock	(40,735)	$ (34)	(40,701)	0	$ 0
Repurchase of common stock (in shares)		(3,419,000)			0
Stock-based compensation	1,598	$ 0	1,598	0	$ 0
Stock-based compensation (in shares)		0			0
Net income	34,865	$ 0	0	34,865	$ 0
Net Income (Shares)		0			0
Balance at Mar. 31, 2023	561,493	$ 659	1,124,709	(170,046)	$ (393,829)
Balance (in shares) at Mar. 31, 2023		65,824,000			32,005,000
Balance at Dec. 31, 2022	$ 565,788	$ 692	1,163,836	(204,911)	$ (393,829)
Balance (in shares) at Dec. 31, 2022	69,188,000	69,188,000			32,005,000
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net income	$ 118,191
Balance at Sep. 30, 2023	$ 627,493	$ 644	1,107,398	(86,720)	$ (393,829)
Balance (in shares) at Sep. 30, 2023	64,384,000	64,384,000			32,005,000
Balance at Mar. 31, 2023	$ 561,493	$ 659	1,124,709	(170,046)	$ (393,829)
Balance (in shares) at Mar. 31, 2023		65,824,000			32,005,000
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding	80	$ 2	78	0	$ 0
Exercise of stock options and issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding		177,000			0
Repurchase of common stock	(9,286)	$ (8)	(9,278)	0	$ 0
Repurchase of common stock (in shares)		(776,000)			0
Stock-based compensation	1,520	$ 0	1,520	0	$ 0
Stock-based compensation (in shares)		0			0
Net income	1,280	$ 0	0	1,280	$ 0
Net Income (Shares)		0			0
Balance at Jun. 30, 2023	555,087	$ 653	1,117,029	(168,766)	$ (393,829)
Balance (in shares) at Jun. 30, 2023		65,225,000			32,005,000
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding	(11)	$ 0	(11)	0	$ 0
Exercise of stock options and issuance of common stock units and stock awards, net of repurchase of shares to satisfy tax withholding		16,000			0
Repurchase of common stock	(11,071)	$ (9)	(11,062)	0	$ 0
Repurchase of common stock (in shares)		(857,000)			0
Stock-based compensation	1,442	$ 0	1,442	0	$ 0
Stock-based compensation (in shares)		0			0
Net income	82,046	$ 0	0	82,046	$ 0
Net Income (Shares)		0			0
Balance at Sep. 30, 2023	$ 627,493	$ 644	$ 1,107,398	$ (86,720)	$ (393,829)
Balance (in shares) at Sep. 30, 2023	64,384,000	64,384,000			32,005,000