Debt - Schedule of Debt (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2022
Debt
Total	$ 453,500		$ 453,500		$ 549,704
Less: Unamortized debt discount and issuance costs	(7,782)		(7,782)		(9,331)
Total debt, net	445,718		445,718		540,373
Less: Current portion of long-term debt, net	0		0		96,193
Total long-term debt, net	445,718		$ 445,718		444,180
HealthCare Royalty Partners
Debt
Maximum potential royalty payout			14.00%
Increase in maximum potential payout percent			4.00%
Maximum aggregate royalty payments			$ 225,000
Required payment for breach of agreement, payment one			125,000
Payment for royalty agreement			17,000
2023 Notes | Convertible subordinated notes
Debt
Total debt	0		0		96,204
2025 Notes | Convertible senior notes
Debt
Total debt	192,500		192,500		192,500
Less: Unamortized debt discount and issuance costs	(1,385)		(1,385)		(1,917)
2028 Notes | Convertible senior notes
Debt
Total debt	261,000		261,000		261,000
Less: Unamortized debt discount and issuance costs	(6,397)		(6,397)		(7,403)
Royalty Financing Agreement | Loans Payable [Member] | HealthCare Royalty Partners
Debt
Interest expense	1,200	$ 1,500	3,700	$ 1,500
Deferred Royalty Obligations	70,100		70,100		70,600
Royalty Payments			$ 4,300
Interest Rate of Deferred Royalty Obligation			7.40%
Royalty Financing Agreement | Loans Payable [Member] | HealthCare Royalty Partners | Other Long Term Liabilities
Debt
Royalty Obligation Payable	66,100		$ 66,100		67,900
Royalty Financing Agreement | Loans Payable [Member] | HealthCare Royalty Partners | Other Accrued Liabilities
Debt
Short term accrued interest	$ 4,000		$ 4,000		$ 2,700