Three Months Ended September 30,

Nine Months Ended September 30,

(In thousands except per share data)

2023

2022

2023

2022

Numerator:

Net income attributable to Innoviva stockholders, basic

$

82,046

$

265,523

$

118,191

$

282,235

Add: interest expense on 2023 Notes, net of tax effect

—

412

86

2,003

Add: interest expense on 2025 Notes, net of tax effect

1,236

994

3,703

3,533

Add: interest expense on 2028 Notes, net of tax effect

1,543

1,769

4,618

3,862

Net income attributable to Innoviva stockholders, diluted

$

84,825

$

268,698

$

126,598

$

291,633

Denominator:

Weighted-average shares used to compute basic net income
   per share attributable to Innoviva stockholders

64,953

69,731

66,016

69,640

Dilutive effect of 2023 Notes

—

4,866

250

6,629

Dilutive effect of 2025 Notes

11,150

11,150

11,150

11,150

Dilutive effect of 2028 Notes

9,955

9,955

9,955

7,559

Dilutive effect of options and awards granted under equity
   incentive plan and employee stock purchase plan

106

128

133

94

Weighted-average shares used to compute diluted net income
   per share attributable to Innoviva stockholders

86,164

95,830

87,504

95,072

Net income per share attributable to Innoviva stockholders

Basic

$

1.26

$

3.81

$

1.79

$

4.05

Diluted

$

0.98

$

2.80

$

1.45

$

3.07