Debt - Schedule of Debt (Details) - USD ($) $ in Thousands	3 Months Ended	6 Months Ended
	Jun. 30, 2023	Jun. 30, 2023	Dec. 31, 2022
Debt
Total	$ 453,500	$ 453,500	$ 549,704
Less: Unamortized debt discount and issuance costs	(8,299)	(8,299)	(9,331)
Total debt, net	445,201	445,201	540,373
Less: Current portion of long-term debt, net	0	0	96,193
Total long-term debt, net	445,201	$ 445,201	444,180
HealthCare Royalty Partners
Debt
Maximum potential royalty payout		14.00%
Increase in maximum potential payout percent		4.00%
Maximum aggregate royalty payments		$ 225,000
Required payment for breach of agreement, payment one		125,000
Payment for royalty agreement		15,400
2023 Notes | Convertible subordinated notes
Debt
Total debt	0	0	96,204
2025 Notes | Convertible senior notes
Debt
Total debt	192,500	192,500	192,500
Less: Unamortized debt discount and issuance costs	(1,563)	(1,563)	(1,917)
2028 Notes | Convertible senior notes
Debt
Total debt	261,000	261,000	261,000
Less: Unamortized debt discount and issuance costs	(6,736)	(6,736)	(7,403)
Royalty Financing Agreement | Loans Payable [Member] | HealthCare Royalty Partners
Debt
Interest expense	1,300	2,500
Deferred Royalty Obligations	70,400	70,400	70,600
Royalty Payments		$ 2,700
Interest Rate of Deferred Royalty Obligation		7.29%
Royalty Financing Agreement | Loans Payable [Member] | HealthCare Royalty Partners | Other Long Term Liabilities
Debt
Royalty Obligation Payable	66,000	$ 66,000	67,900
Royalty Financing Agreement | Loans Payable [Member] | HealthCare Royalty Partners | Other Accrued Liabilities
Debt
Short term accrued interest	$ 4,400	$ 4,400	$ 2,700