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Equity and Long-term Investments and Fair Value Measurements - Schedule of Available-for-Sale Securities Measured at Fair Value on a Recurring Basis (Details) - USD ($)
$ in Thousands
6 Months Ended 12 Months Ended
Jun. 30, 2023
Dec. 31, 2022
Financial Instruments and Fair Value Measurements    
Contingent value rights $ 595 $ 595
ISP Fund LP    
Liabilities    
Lock-up period 36 months 36 months
Contributed to partnership for investing $ 300,000 $ 300,000
ISP Fund LP | Convertible Debt    
Assets    
Total assets measured at estimated fair value 55,400  
Money market funds | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 7,200 25,100
Equity investment | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 319,400 295,400
Private Placement Positions and Convertible Notes | ISP Fund LP    
Assets    
Total assets measured at estimated fair value   54,600
Recurring basis    
Assets    
Total assets measured at estimated fair value 471,331 639,488
Recurring basis | Money market funds    
Assets    
Total assets measured at estimated fair value 118,931 263,469
Recurring basis | Equity investments and money market funds | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 264,021 [1] 320,560 [2]
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1    
Assets    
Total assets measured at estimated fair value 409,513 560,546
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Money market funds    
Assets    
Total assets measured at estimated fair value 118,931 263,469
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investments and money market funds | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 261,994 [1] 265,982 [2]
Recurring basis | Significant Other Observable Inputs, Level 2    
Assets    
Total assets measured at estimated fair value 6,473 8,059
Recurring basis | Significant Other Observable Inputs, Level 2 | Money market funds    
Assets    
Total assets measured at estimated fair value 0 0
Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investments and money market funds | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 0 [1] 0 [2]
Recurring basis | Significant Unobservable Inputs, Level 3    
Assets    
Total assets measured at estimated fair value 55,345 70,883
Recurring basis | Significant Unobservable Inputs, Level 3 | Money market funds    
Assets    
Total assets measured at estimated fair value 0 0
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investments and money market funds | ISP Fund LP    
Assets    
Total assets measured at estimated fair value 2,027 [1] 54,578 [2]
Nonrecurring basis    
Financial Instruments and Fair Value Measurements    
Contingent value rights 595 595
Liabilities    
Total liabilities measured at estimated fair value 406,531 506,259
Nonrecurring basis | Debt    
Financial Instruments and Fair Value Measurements    
2023 Notes   96,089
2025 Notes 189,915 197,807
2028 Notes 216,021 211,768
Total fair value of debt 405,936 505,664
Nonrecurring basis | Quoted Price in Active Markets for Identical Assets, Level 1    
Financial Instruments and Fair Value Measurements    
Contingent value rights 0 0
Liabilities    
Total liabilities measured at estimated fair value 0 0
Nonrecurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Debt    
Financial Instruments and Fair Value Measurements    
2023 Notes   0
2025 Notes 0 0
2028 Notes 0 0
Total fair value of debt 0 0
Nonrecurring basis | Significant Other Observable Inputs, Level 2    
Financial Instruments and Fair Value Measurements    
Contingent value rights 0 0
Liabilities    
Total liabilities measured at estimated fair value 405,936 505,664
Nonrecurring basis | Significant Other Observable Inputs, Level 2 | Debt    
Financial Instruments and Fair Value Measurements    
2023 Notes   96,089
2025 Notes 189,915 197,807
2028 Notes 216,021 211,768
Total fair value of debt 405,936 505,664
Nonrecurring basis | Significant Unobservable Inputs, Level 3    
Financial Instruments and Fair Value Measurements    
Contingent value rights 595 595
Liabilities    
Total liabilities measured at estimated fair value 595 595
Nonrecurring basis | Significant Unobservable Inputs, Level 3 | Debt    
Financial Instruments and Fair Value Measurements    
2023 Notes   0
2025 Notes 0 0
2028 Notes 0 0
Total fair value of debt 0 0
Armata | Recurring basis | Convertible Debt    
Assets    
Total assets measured at estimated fair value 31,173  
Armata | Recurring basis | Equity investment | Common stock    
Assets    
Total assets measured at estimated fair value 28,588 31,095
Armata | Recurring basis | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 6,473 8,059
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Convertible Debt    
Assets    
Total assets measured at estimated fair value 0  
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock    
Assets    
Total assets measured at estimated fair value 28,588 31,095
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 0 0
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Convertible Debt    
Assets    
Total assets measured at estimated fair value 0  
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Common stock    
Assets    
Total assets measured at estimated fair value 0 0
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 6,473 8,059
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Convertible Debt    
Assets    
Total assets measured at estimated fair value 31,173  
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Common stock    
Assets    
Total assets measured at estimated fair value 0 0
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value 0 0
InCarda | Recurring basis | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value   605
InCarda | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value   0
InCarda | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value   0
InCarda | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants    
Assets    
Total assets measured at estimated fair value   605
Gate Neuroscience Member | Recurring basis | Convertible Debt    
Assets    
Total assets measured at estimated fair value 22,145 15,700
Gate Neuroscience Member | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Convertible Debt    
Assets    
Total assets measured at estimated fair value 0 0
Gate Neuroscience Member | Recurring basis | Significant Other Observable Inputs, Level 2 | Convertible Debt    
Assets    
Total assets measured at estimated fair value 0 0
Gate Neuroscience Member | Recurring basis | Significant Unobservable Inputs, Level 3 | Convertible Debt    
Assets    
Total assets measured at estimated fair value $ 22,145 $ 15,700
[1] The investments held by ISP Fund LP consisted of $319.4 million in equity investments, which included $7.2 million in money market funds, and $55.4 million receivable from the maturity of convertible notes. Our total capital contribution of $300 million is subject to a 36-month lock-up period from the date of such capital contributions.
[2] The investments held by ISP Fund LP consisted of $295.4 million equity investments, which included private placement positions and convertible notes of $54.6 million, and $25.1 million in money market funds. Our total capital contributions of $300.0 million is subject to a 36-month lock-up period from the date of such capital contributions.