EQUITY AND LONG-TERM INVESTMENTS AND FAIR VALUE MEASUREMENTS - Schedule of Available-for-Sale Securities Measured at Fair Value on a Recurring Basis (Details) - USD ($) $ in Thousands		12 Months Ended
		Dec. 31, 2022		Dec. 31, 2021
Fair Value Measurements
Contingent value rights liability		$ 595
ISP Fund LP
Liabilities
Lock-up period		36 months		36 months
Contributed to partnership for investing		$ 300,000
Money market funds | ISP Fund LP
Assets
Total assets measured at estimated fair value		25,100		$ 3,500
Equity investment | ISP Fund LP
Assets
Total assets measured at estimated fair value		295,400		192,200
Private Placement Positions And Convertible Notes | ISP Fund LP
Assets
Total assets measured at estimated fair value		54,600
Recurring basis
Assets
Total assets measured at estimated fair value		639,488		606,792
Recurring basis | Money market funds
Assets
Total assets measured at estimated fair value		263,469		145,132
Recurring basis | Equity investments and Money market funds | ISP Fund LP
Assets
Total assets measured at estimated fair value		320,560	[1]	195,745	[2]
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1
Assets
Total assets measured at estimated fair value		560,546		489,704
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | ISP Fund LP
Assets
Total assets measured at estimated fair value	[1]	265,982
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Money market funds
Assets
Total assets measured at estimated fair value		263,469		145,132
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investments and Money market funds | ISP Fund LP
Assets
Total assets measured at estimated fair value	[2]			193,677
Recurring basis | Significant Other Observable Inputs, Level 2
Assets
Total assets measured at estimated fair value		8,059		99,509
Recurring basis | Significant Unobservable Inputs, Level 3
Assets
Total assets measured at estimated fair value		70,883		17,579
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investments and Money market funds | ISP Fund LP
Assets
Total assets measured at estimated fair value		54,578	[1]	2,068	[2]
Nonrecurring basis
Fair Value Measurements
Contingent value rights liability		595
Liabilities
Total liabilities at estimated fair value		506,259
Nonrecurring basis | Debt
Fair Value Measurements
2023 Notes		96,089		261,769
2025 Notes		197,807		234,498
2028 Notes		211,768
Total fair value of debt		505,664		496,267
Nonrecurring basis | Significant Other Observable Inputs, Level 2
Fair Value Measurements
2028 Notes		211,768
Total fair value of debt		505,664
Liabilities
Total liabilities at estimated fair value		505,664
Nonrecurring basis | Significant Other Observable Inputs, Level 2 | Debt
Fair Value Measurements
2023 Notes		96,089		261,769
2025 Notes		197,807		234,498
Total fair value of debt				496,267
Nonrecurring basis | Significant Unobservable Inputs, Level 3
Fair Value Measurements
Contingent value rights liability		595
Liabilities
Total liabilities at estimated fair value		595
Armata | Recurring basis | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		31,095		88,101
Armata | Recurring basis | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		8,059		58,595
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		31,095		88,101
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		8,059		58,595
Entasis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock
Assets
Total assets measured at estimated fair value				62,794
Entasis | Recurring basis | Equity investment | Common stock
Assets
Total assets measured at estimated fair value				62,794
Entasis | Recurring basis | Equity investment | Warrants
Assets
Total assets measured at estimated fair value				40,914
Entasis | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value				40,914
InCarda | Recurring basis | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		605		411
InCarda | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		605		411
Gate Neurosciences Member | Recurring basis | Convertible debt investment
Assets
Total assets measured at estimated fair value		15,700		15,100
Gate Neurosciences Member | Recurring basis | Significant Unobservable Inputs, Level 3 | Convertible debt investment
Assets
Total assets measured at estimated fair value		$ 15,700		$ 15,100

[1] The investments held by ISP Fund LP, consisted of $295.4 million in equity investments, which included private placement positions and convertible notes of $54.6 million, and $25.1 million in money market funds. Our total capital contribution of $300.0 million is subject to a 36-month lock-up period from the date of such capital contributions.

[2] The investments held by ISP Fund LP, consisted of $192.2 million equity investments and $3.5 million money market funds, are subject to a 36-month lock-up period from our initial contribution date, December 11, 2020.