Commitments and Contingencies (Additional Information) (Details)	3 Months Ended
Mar. 31, 2022 ft²
Entasis Lease
Lessee, Lease, Description [Line Items]
Operating lease, Weighted average remaining lease term	3 years 9 months 18 days
Operating lease, weighted average incremental borrowing rate	7.80%
Waltham, Massachusetts
Lessee, Lease, Description [Line Items]
Lease space	20,062
Burlingame, California
Lessee, Lease, Description [Line Items]
Lease space	2,111

Weighted average remaining lease term for operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 55
-Paragraph 53
-URI http://asc.fasb.org/extlink&oid=123414884&loc=SL77918982-209971

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 4
-Subparagraph (g)(3)
-URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918686-209980

Name:	us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	instant