FINANCIAL INSTRUMENTS AND FAIR VALUE MEASUREMENTS - Fair Value Measurements (Details) - USD ($) $ in Thousands	Dec. 11, 2020	Dec. 31, 2021	Dec. 31, 2020
ISP Fund LP
Debt
Lock-up period	36 months
Money market funds | ISP Fund LP
Assets
Total assets measured at estimated fair value		$ 3,500	$ 284,800
Equity investment | ISP Fund LP
Assets
Total assets measured at estimated fair value		192,200	14,500
Recurring basis
Assets
Total assets measured at estimated fair value		606,792	627,254
Recurring basis | Money market funds
Assets
Total assets measured at estimated fair value		145,132	204,808
Recurring basis | Equity investments and Money market funds | ISP Fund LP
Assets
Total assets measured at estimated fair value		195,745	299,288
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1
Assets
Total assets measured at estimated fair value		489,704	576,176
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Money market funds
Assets
Total assets measured at estimated fair value		145,132	204,808
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investments and Money market funds | ISP Fund LP
Assets
Total assets measured at estimated fair value		193,677	299,288
Recurring basis | Significant Other Observable Inputs, Level 2
Assets
Total assets measured at estimated fair value		99,509	49,931
Recurring basis | Significant Other Observable Inputs, Level 2 | Money market funds
Assets
Total assets measured at estimated fair value		0	0
Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investments and Money market funds | ISP Fund LP
Assets
Total assets measured at estimated fair value		0	0
Recurring basis | Significant Unobservable Inputs, Level 3
Assets
Total assets measured at estimated fair value		17,579	1,147
Recurring basis | Significant Unobservable Inputs, Level 3 | Money market funds
Assets
Total assets measured at estimated fair value		0	0
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investments and Money market funds | ISP Fund LP
Assets
Total assets measured at estimated fair value		2,068	0
Nonrecurring basis | Debt
Debt
2023 Notes		261,769	239,779
2025 Notes		234,498	206,135
Total fair value of debt		496,267	445,914
Nonrecurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Debt
Debt
2023 Notes		0	0
2025 Notes		0	0
Total fair value of debt		0	0
Nonrecurring basis | Significant Other Observable Inputs, Level 2 | Debt
Debt
2023 Notes		261,769	239,779
2025 Notes		234,498	206,135
Total fair value of debt		496,267	445,914
Nonrecurring basis | Significant Unobservable Inputs, Level 3 | Debt
Debt
2023 Notes		0	0
2025 Notes		0	0
Total fair value of debt		0	0
Armata | Recurring basis | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		88,101	25,958
Armata | Recurring basis | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		58,595	18,049
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		88,101	25,958
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		0	0
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		0	0
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		58,595	18,049
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		0	0
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		0	0
Entasis | Recurring basis | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		62,794	46,122
Entasis | Recurring basis | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		40,914	31,882
Entasis | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		62,794	46,122
Entasis | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		0	0
Entasis | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		0
Entasis | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		40,914	31,882
Entasis | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Common stock
Assets
Total assets measured at estimated fair value		0	0
Entasis | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		0	0
InCarda | Recurring basis | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		411	1,147
InCarda | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		0	0
InCarda | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		0	0
InCarda | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants
Assets
Total assets measured at estimated fair value		411	$ 1,147
Gate Neurosciences | Recurring basis | Convertible debt investment
Assets
Total assets measured at estimated fair value		15,100
Gate Neurosciences | Recurring basis | Significant Unobservable Inputs, Level 3 | Convertible debt investment
Assets
Total assets measured at estimated fair value		$ 15,100