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FINANCIAL INSTRUMENTS AND FAIR VALUE MEASUREMENTS - Convertible Promissory Note in Gate Neurosciences (Details) - USD ($)
$ in Thousands
12 Months Ended
Nov. 24, 2021
Dec. 31, 2021
Dec. 31, 2020
Debt Instrument [Line Items]      
Number of common stock issued description The number of common stock shares to be issued in a qualified event shall be equal to the amount due on the conversion date divided by the lesser of a capped conversion price (the "Capped Conversion Price") and the qualified event price (the "Qualified Event Price"). The Capped Conversion Price is calculated as $50.0 million divided by the number of common stock outstanding at such time on a fully diluted basis. The Qualified Event Price is the price per share determined by the qualified event. A qualified financing is a sale or series of sales of preferred stock where (i) at least 50 percent of counterparties are not existing shareholders, (ii) net proceeds to Gate are at least $35.0 million, and (iii) the stated or implied equity valuation of Gate is at least $80.0 million. Shadow Preferred means preferred stock having identical rights, preferences and restrictions as the preferred stock that would be issued in a qualified financing.    
Long-term Investments   $ 483,845 $ 438,258
Gate Neuroscience [Member]      
Debt Instrument [Line Items]      
Debt Instrument Transaction Cost   900  
Unrealized loss from fair value changes in equity investments   800  
Long-term Investments   $ 15,900  
Gate Neuroscience [Member] | Common Stock [Member]      
Debt Instrument [Line Items]      
Debt Instrument, Interest Rate, Effective Percentage 8.00%    
Convertible Promissory Note Purchase Agreement [Member] | Gate Neuroscience [Member]      
Debt Instrument [Line Items]      
Debt Instrument, Principal Payment $ 15,000