CONSOLIDATED STATEMENTS OF INCOME - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Revenue:
Total net revenue	$ 391,866	$ 336,794	$ 261,016
Operating expenses:
Research and development	576	1,788	0
General and administrative	16,187	13,883	14,656
Total operating expenses	16,763	15,671	14,656
Income from operations	375,103	321,123	246,360
Interest and dividend income	1,839	1,524	5,540
Other expense, net	(3,626)	(348)	(345)
Interest expense	(19,070)	(18,331)	(18,660)
Realized gain on equity investments	91,030	50,277	0
Income before income taxes	445,276	354,245	232,895
Income tax expense, net	76,439	60,431	41,902
Net income	368,837	293,814	190,993
Net income attributable to noncontrolling interest	102,983	69,412	33,705
Net income attributable to Innoviva stockholders	$ 265,854	$ 224,402	$ 157,288
Basic net income per share attributable to Innoviva stockholders	$ 3.24	$ 2.21	$ 1.55
Diluted net income per share attributable to Innoviva stockholders	$ 2.87	$ 2.02	$ 1.43
Shares used to compute Innoviva basic and diluted net income per share:
Shares used to compute basic net income per share	82,062	101,320	101,150
Shares used to compute diluted net income per share	94,310	113,554	113,409
Royalty revenue from a related party
Revenue:
Total net revenue	$ 391,866	$ 326,794	$ 261,016
Revenue from collaborative arrangements
Revenue:
Total net revenue	$ 0	$ 10,000	$ 0