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Financial Instruments and Fair Value Measurements - Fair Value Measurements (Details) - USD ($)
$ in Thousands
Dec. 11, 2020
Sep. 30, 2021
Dec. 31, 2020
ISP Fund LP      
Debt      
Lock-up period 36 months    
Recurring basis      
Assets      
Total assets measured at estimated fair value   $ 562,956 $ 627,254
Recurring basis | Money market funds      
Assets      
Total assets measured at estimated fair value   78,025 204,808
Recurring basis | Equity investments and money market funds | ISP Fund LP      
Assets      
Total assets measured at estimated fair value   228,946 299,288
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1      
Assets      
Total assets measured at estimated fair value   454,450 576,176
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Money market funds      
Assets      
Total assets measured at estimated fair value   78,025 204,808
Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investments and money market funds | ISP Fund LP      
Assets      
Total assets measured at estimated fair value   226,848 299,288
Recurring basis | Significant Other Observable Inputs, Level 2      
Assets      
Total assets measured at estimated fair value   105,850 49,931
Recurring basis | Significant Other Observable Inputs, Level 2 | Money market funds      
Assets      
Total assets measured at estimated fair value   0 0
Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investments and money market funds | ISP Fund LP      
Assets      
Total assets measured at estimated fair value   0 0
Recurring basis | Significant Unobservable Inputs, Level 3      
Assets      
Total assets measured at estimated fair value   2,656 1,147
Recurring basis | Significant Unobservable Inputs, Level 3 | Money market funds      
Assets      
Total assets measured at estimated fair value   0 0
Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investments and money market funds | ISP Fund LP      
Assets      
Total assets measured at estimated fair value   2,098 0
Nonrecurring basis | Debt      
Debt      
2023 Notes   259,142 239,779
2025 Notes   231,418 206,135
Total fair value of debt   490,560 445,914
Nonrecurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Debt      
Debt      
2023 Notes   0 0
2025 Notes   0 0
Total fair value of debt   0 0
Nonrecurring basis | Significant Other Observable Inputs, Level 2 | Debt      
Debt      
2023 Notes   259,142 239,779
2025 Notes   231,418 206,135
Total fair value of debt   490,560 445,914
Nonrecurring basis | Significant Unobservable Inputs, Level 3 | Debt      
Debt      
2023 Notes   0 0
2025 Notes   0 0
Total fair value of debt   0 0
Armata | Recurring basis | Equity investment | Common stock      
Assets      
Total assets measured at estimated fair value   53,810 25,958
Armata | Recurring basis | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   35,470 18,049
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock      
Assets      
Total assets measured at estimated fair value   53,810 25,958
Armata | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   0 0
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Common stock      
Assets      
Total assets measured at estimated fair value   0 0
Armata | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   35,470 18,049
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Common stock      
Assets      
Total assets measured at estimated fair value   0 0
Armata | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   0 0
Entasis | Recurring basis | Equity investment | Common stock      
Assets      
Total assets measured at estimated fair value   95,767 46,122
Entasis | Recurring basis | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   70,380 31,882
Entasis | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Common stock      
Assets      
Total assets measured at estimated fair value   95,767 46,122
Entasis | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   0 0
Entasis | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Common stock      
Assets      
Total assets measured at estimated fair value   0 0
Entasis | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   70,380 31,882
Entasis | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Common stock      
Assets      
Total assets measured at estimated fair value   0 0
Entasis | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   0 0
InCarda | Recurring basis | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   558 1,147
InCarda | Recurring basis | Quoted Price in Active Markets for Identical Assets, Level 1 | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   0 0
InCarda | Recurring basis | Significant Other Observable Inputs, Level 2 | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   0 0
InCarda | Recurring basis | Significant Unobservable Inputs, Level 3 | Equity investment | Warrants      
Assets      
Total assets measured at estimated fair value   $ 558 $ 1,147