-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 EHaNCDyWTbfh3xaWH1KIoryssjLMwzDh3++FJl9S0bguql8J1jj4LXqLINUsCfY9
 0Is6naz6pW9YxRtnEbh9oA==

<SEC-DOCUMENT>0001144204-09-017106.txt : 20090330
<SEC-HEADER>0001144204-09-017106.hdr.sgml : 20090330
<ACCEPTANCE-DATETIME>20090330172047
ACCESSION NUMBER:		0001144204-09-017106
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20090330
DATE AS OF CHANGE:		20090330
EFFECTIVENESS DATE:		20090330

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NEOGENOMICS INC
		CENTRAL INDEX KEY:			0001077183
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-TESTING LABORATORIES [8734]
		IRS NUMBER:				742897368
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-51319
		FILM NUMBER:		09715141

	BUSINESS ADDRESS:	
		STREET 1:		1726 MEDICAL BOULEVARD, SUITE 201
		STREET 2:		SUITE 201
		CITY:			NAPLES
		STATE:			FL
		ZIP:			34108
		BUSINESS PHONE:		9419231949

	MAIL ADDRESS:	
		STREET 1:		1726 MEDICAL BOULEVARD, SUITE 201
		STREET 2:		SUITE 201
		CITY:			NAPLES
		STATE:			FL
		ZIP:			34108

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AMERICAN COMMUNICATIONS ENTERPRISES INC
		DATE OF NAME CHANGE:	19990120
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0301</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001077183</cik>
        <entityName>NEOGENOMICS INC</entityName>
        <issuerAddress>
            <street1>12701 Commonwealth Drive, Suite 9</street1>
            <city>Ft. Myers</city>
            <stateOrCountry>FL</stateOrCountry>
            <zipCode>33913</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>239-768-0600</issuerPhoneNumber>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <jurisdictionOfInc>NV</jurisdictionOfInc>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <middleName>P.</middleName>
                <lastName>Gasparini</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Steven</firstName>
                <middleName>C.</middleName>
                <lastName>Jones</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Michael</firstName>
                <middleName>T.</middleName>
                <lastName>Dent</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>George</firstName>
                <middleName>G.</middleName>
                <lastName>O'Leary</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Peter</firstName>
                <middleName>M.</middleName>
                <lastName>Peterson</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Marvin</firstName>
                <middleName>E.</middleName>
                <lastName>Jaffe</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>William</firstName>
                <middleName>J.</middleName>
                <lastName>Robison</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <middleName>J.</middleName>
                <lastName>Feeney</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Matthew</firstName>
                <middleName>William</middleName>
                <lastName>Moore</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jerome</firstName>
                <middleName>J.</middleName>
                <lastName>Dvonch</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Douglas</firstName>
                <middleName>M.</middleName>
                <lastName>Van Oort</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>12701 Commonwealth Drive, Suite 9</street1>
                <city>Ft. Myers</city>
                <stateOrCountry>FL</stateOrCountry>
                <zipCode>33913</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Other Health Care</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$5,000,001 - $25,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-03-16</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>1156250</totalOfferingAmount>
            <totalAmountSold>500000</totalAmountSold>
            <totalRemaining>656250</totalRemaining>
            <clarificationOfResponse>Includes up to 625,000 shares issuable upon exercise of a warrant with an exercise price of $1.05 per share</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>1</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>true</authorizedRepresentative>
            <signature>
                <issuerName>NEOGENOMICS, INC.</issuerName>
                <signatureName>/s/ Jerome J. Dvonch</signatureName>
                <nameOfSigner>Jerome J. Dvonch</nameOfSigner>
                <signatureTitle>Principal Accounting Officer</signatureTitle>
                <signatureDate>2009-03-30</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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