CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022
CASH FLOWS FROM OPERATING ACTIVITIES
Net loss	$ (55,126)	$ (84,711)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	18,523	16,921
Amortization of intangibles	17,566	16,979
Non-cash stock-based compensation	10,463	15,729
Non-cash operating lease expense	4,648	4,989
Amortization of convertible debt discount	1,341	1,324
Amortization of debt issue costs	92	91
Gain on sale of assets held for sale	0	(2,048)
Other adjustments	1,665	1,602
Changes in assets and liabilities, net
Accounts receivable, net	(5,713)	854
Inventories	(888)	1,533
Prepaid and other assets	(2,614)	(2,202)
Operating lease liabilities	(3,294)	(4,932)
Deferred income tax liabilities, net	(5,939)	(9,495)
Accrued compensation	5,545	(1,024)
Accounts payable and other liabilities	(509)	(1,646)
Net cash used in operating activities	(14,240)	(46,036)
CASH FLOWS FROM INVESTING ACTIVITIES
Purchases of marketable securities	(6,756)	(56,332)
Proceeds from sales and maturities of marketable securities	62,868	68,525
Purchases of property and equipment	(17,421)	(18,513)
Proceeds from assets held for sale	0	12,098
Net cash provided by investing activities	38,691	5,778
CASH FLOWS FROM FINANCING ACTIVITIES
Repayment of equipment financing obligations	(61)	(574)
Issuance of common stock, net	1,504	7,642
Net cash provided by financing activities	1,443	7,068
Net change in cash and cash equivalents	25,894	(33,190)
Cash and cash equivalents, beginning of period	263,180	316,827
Cash and cash equivalents, end of period	289,074	283,637
Supplemental disclosure of cash flow information:
Interest paid	1,690	2,143
Income taxes paid, net	175	129
Supplemental disclosure of non-cash investing and financing information:
Purchases of property and equipment included in accounts payable	$ 838	$ 1,529