CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Current assets
Cash and cash equivalents	$ 275,609	$ 263,180
Marketable securities, at fair value	142,306	174,809
Accounts receivable, net	118,842	119,711
Inventories	24,432	24,277
Prepaid assets	16,185	15,237
Other current assets	7,622	8,077
Total current assets	584,996	605,291
Property and equipment (net of accumulated depreciation of $138,863 and $131,930, respectively)	102,845	102,499
Operating lease right-of-use assets	93,784	96,109
Intangible assets, net	399,477	408,260
Goodwill	522,766	522,766
Other assets	5,306	5,109
Total non-current assets	1,124,178	1,134,743
Total assets	1,709,174	1,740,034
Current liabilities
Accounts payable	22,712	20,510
Accrued compensation	32,891	40,141
Accrued expenses and other liabilities	17,964	15,070
Current portion of equipment financing obligations	38	70
Current portion of operating lease liabilities	6,934	6,584
Pharma contract liabilities	6,067	7,557
Total current liabilities	86,606	89,932
Long-term liabilities
Convertible senior notes, net	536,037	535,322
Operating lease liabilities	67,319	68,952
Deferred income tax liabilities, net	31,715	34,750
Other long-term liabilities	13,035	13,055
Total long-term liabilities	648,106	652,079
Total liabilities	734,712	742,011
Commitments and contingencies (Note 11)
Stockholders’ equity
Common stock, $0.001 par value, (250,000,000 shares authorized; 127,200,491 and 126,913,992 shares issued and outstanding, respectively)	127	127
Additional paid-in capital	1,167,051	1,160,882
Accumulated other comprehensive loss	(2,834)	(3,899)
Accumulated deficit	(189,882)	(159,087)
Total stockholders’ equity	974,462	998,023
Total liabilities and stockholders’ equity	$ 1,709,174	$ 1,740,034