Stock-Based Compensation - Summary of Stock Option Activity (Details)	3 Months Ended
	Mar. 31, 2022 $ / shares shares
Number of shares
Beginning balance (in shares) | shares	2,961,195
Options granted (in shares) | shares	1,218,481
Less:
Options exercised (in shares) | shares	471,609
Options canceled or expired (in shares) | shares	747,269
Ending balance (in shares) | shares	2,960,798
Exercisable at end of period (in shares) | shares	1,343,021
Weighted Average Exercise Price
Weighted average exercise price, beginning balance (in dollars per share) | $ / shares	$ 25.46
Weighted average exercise price, granted (in dollars per share) | $ / shares	25.03
Less:
Weighted average exercise price, exercised (in dollars per share) | $ / shares	13.70
Weighted average exercise price, canceled or expired (in dollars per share) | $ / shares	29.56
Weighted average exercise price, ending balance (in dollars per share) | $ / shares	26.11
Weighted average exercise price, exercisable, ending balance (in dollars per share) | $ / shares	$ 19.37