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Investment in Non-Consolidated Affiliate (Details)
$ in Thousands
3 Months Ended 12 Months Ended
Sep. 30, 2021
USD ($)
Jun. 18, 2021
USD ($)
May 22, 2020
USD ($)
Mar. 31, 2021
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
May 22, 2021
USD ($)
Jan. 31, 2021
USD ($)
May 31, 2020
USD ($)
Schedule of Equity Method Investments [Line Items]                    
Carrying amount of investment in non-consolidated affiliate         $ 1,869,778 $ 988,331        
Investment in non-consolidated affiliate         0 29,555        
Gain on settlement under line of credit         4,700          
Gain on investment in and loan receivable from non-consolidated affiliate, net         109,260 3,955 $ 0      
Inivata                    
Schedule of Equity Method Investments [Line Items]                    
Fair value of previously-held equity interest $ 64,900 $ 64,906                
Fair value of Purchase Option $ 74,300 74,300                
Unrealized gain on investment in non-consolidated affiliate, net         104,600          
Measurement period adjustments, net assets acquired   17,750     17,800          
Gain on investment in and loan receivable from non-consolidated affiliate, net         $ 109,300 4,000        
Variable Interest Entity, Not Primary Beneficiary                    
Schedule of Equity Method Investments [Line Items]                    
Carrying amount of investment in non-consolidated affiliate           29,600        
Unrealized gain on remeasurement           4,000        
Preference Shares | Variable Interest Entity, Not Primary Beneficiary                    
Schedule of Equity Method Investments [Line Items]                    
Carrying amount of investment in non-consolidated affiliate           25,000        
Investment in non-consolidated affiliate                 $ 30,000  
Preference Shares | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Risk Free Interest Rate                    
Schedule of Equity Method Investments [Line Items]                    
Purchase option, measurement input (as a percent)         0.0017          
Preference Shares | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Price Volatility                    
Schedule of Equity Method Investments [Line Items]                    
Purchase option, measurement input (as a percent)         0.840          
Preference Shares | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Expected Dividend Rate                    
Schedule of Equity Method Investments [Line Items]                    
Purchase option, measurement input (as a percent)         0.000          
Purchase Option | Variable Interest Entity, Not Primary Beneficiary                    
Schedule of Equity Method Investments [Line Items]                    
Carrying amount of investment in non-consolidated affiliate           $ 4,600        
Purchase Option | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Risk Free Interest Rate                    
Schedule of Equity Method Investments [Line Items]                    
Purchase option, measurement input (as a percent)         0.0017 0.0017        
Purchase Option | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Price Volatility                    
Schedule of Equity Method Investments [Line Items]                    
Purchase option, measurement input (as a percent)         0.840 0.840        
Purchase Option | Variable Interest Entity, Not Primary Beneficiary | Measurement Input, Expected Dividend Rate                    
Schedule of Equity Method Investments [Line Items]                    
Purchase option, measurement input (as a percent)         0.000 0.000        
Affiliated Entity                    
Schedule of Equity Method Investments [Line Items]                    
Net unrealized loss from remeasurement of investment       $ 5,000            
Amount outstanding under line of credit   10,300                
Affiliated Entity | Line of Credit                    
Schedule of Equity Method Investments [Line Items]                    
Line of credit facility maximum borrowing capacity     $ 15,000         $ 15,000    
Interest rate per annum (as a percent)         0.00%          
Imputed interest rate (as a percent)                 8.33%  
Loan with imputed interest, discount)                 $ 5,000  
Additional investment in non-consolidated affiliate                 5,000  
Present value of loan receivable with imputed interest                 $ 10,000  
Amount outstanding under line of credit   10,300                
Affiliated Entity | Variable Interest Entity, Not Primary Beneficiary                    
Schedule of Equity Method Investments [Line Items]                    
Investment in minority interest   29,600 25,000 29,600           $ 25,000
Transaction costs     600              
Affiliated Entity | Variable Interest Entity, Not Primary Beneficiary | Line of Credit                    
Schedule of Equity Method Investments [Line Items]                    
Interest income from loan receivable         $ 400          
Affiliated Entity | Preference Shares | Variable Interest Entity, Not Primary Beneficiary                    
Schedule of Equity Method Investments [Line Items]                    
Investment in minority interest   25,000 19,600 25,000            
Affiliated Entity | Purchase Option | Variable Interest Entity, Not Primary Beneficiary                    
Schedule of Equity Method Investments [Line Items]                    
Investment in minority interest   $ 4,600 $ 6,000 $ 4,600