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Acquisitions - Narrative (Details) - USD ($)
1 Months Ended 12 Months Ended
Sep. 30, 2021
Jun. 18, 2021
Apr. 07, 2021
Apr. 30, 2021
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Mar. 31, 2021
May 31, 2020
May 22, 2020
Business Acquisition [Line Items]                    
Cash paid at closing         $ 419,404,000 $ 37,000,000 $ 0      
Common stock, par value (in dollars per share)         $ 0.001 $ 0.001        
Gain on investment in and loan receivable from non-consolidated affiliate, net         $ 109,260,000 $ 3,955,000 0      
Goodwill         527,115,000 211,083,000        
Clinical Services                    
Business Acquisition [Line Items]                    
Goodwill         462,603,000 179,534,000        
Pharma Services                    
Business Acquisition [Line Items]                    
Goodwill         $ 64,512,000 31,549,000        
Affiliated Entity                    
Business Acquisition [Line Items]                    
Amount outstanding under line of credit   $ 10,300,000                
Variable Interest Entity, Not Primary Beneficiary | Affiliated Entity                    
Business Acquisition [Line Items]                    
Investment in minority interest   29,600,000           $ 29,600,000 $ 25,000,000 $ 25,000,000
Consideration paid to other shareholders   390,000,000                
Identifiable intangible assets - developed technology | Maximum                    
Business Acquisition [Line Items]                    
Amortization period         15 years          
Marketing Assets                    
Business Acquisition [Line Items]                    
Amortization period         4 years          
Trademarks                    
Business Acquisition [Line Items]                    
Amortization period         15 years          
Trade Name                    
Business Acquisition [Line Items]                    
Amortization period         5 years          
Trapelo Health                    
Business Acquisition [Line Items]                    
Voting interests acquired (as a percent)     100.00%              
Cash paid at closing     $ 35,591,000              
Payments to acquire business, adjustments     600,000              
Common stock issued for consideration     $ 29,174,000              
Common stock issued (in shares)     597,712 597,712            
Share price (in dollars per share)     $ 48.81              
Amortization period     9 years 9 months 18 days              
Goodwill, expected tax deductible amount     $ 0              
Acquisition and integration costs         $ 1,800,000 0 0      
Goodwill     $ 44,664,000              
Goodwill acquired         44,664,000          
Trapelo Health | Clinical Services                    
Business Acquisition [Line Items]                    
Goodwill acquired         44,664,000          
Trapelo Health | Pharma Services                    
Business Acquisition [Line Items]                    
Goodwill acquired         0          
Trapelo Health | Identifiable intangible assets - developed technology                    
Business Acquisition [Line Items]                    
Intangible assets, useful life     10 years              
Trapelo Health | Marketing Assets                    
Business Acquisition [Line Items]                    
Intangible assets, useful life     4 years              
Inivata                    
Business Acquisition [Line Items]                    
Cash paid at closing   398,594,000                
Payments to acquire business, adjustments   $ 8,600,000                
Amortization period   14 years 10 months 24 days                
Goodwill, expected tax deductible amount   $ 0                
Acquisition and integration costs         (13,900,000) 0 $ 0      
Lin of credit settled as consideration for acquisition   15,000,000                
Fair value of previously-held equity interest $ 64,900,000 64,906,000                
Fair value of Purchase Option $ 74,300,000 74,300,000                
Gain on investment in and loan receivable from non-consolidated affiliate, net         109,300,000 $ 4,000,000        
Measurement period adjustments, net assets acquired   17,750,000     17,800,000          
Goodwill   271,368,000                
Goodwill acquired         271,368,000          
Deferred income tax liabilities   $ (60,994,000)                
Revenue from acquiree         1,500,000          
Net loss from acquiree         27,600,000          
Acquisition related costs         11,000,000          
Inivata | Clinical Services                    
Business Acquisition [Line Items]                    
Goodwill acquired         238,405,000          
Inivata | Pharma Services                    
Business Acquisition [Line Items]                    
Goodwill acquired         $ 32,963,000          
Inivata | Identifiable intangible assets - developed technology | Maximum                    
Business Acquisition [Line Items]                    
Intangible assets, useful life   15 years                
Inivata | Trademarks | Maximum                    
Business Acquisition [Line Items]                    
Intangible assets, useful life   15 years                
Inivata | Trade Name                    
Business Acquisition [Line Items]                    
Intangible assets, useful life   5 years