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Segment Information (Tables)
12 Months Ended
Dec. 31, 2021
Segment Reporting [Abstract]  
Schedule of Segment Reporting Information, by Segment
The following table summarizes segment information for the years ended December 31, 2021, 2020 and 2019 (in thousands):
 202120202019
Net revenue:
Clinical Services$404,172 $382,337 $361,161 
Pharma Services80,157 62,111 47,669 
Total net revenue484,329 444,448 408,830 
Cost of revenue:
Clinical Services(1)
244,360 215,529 185,612 
Pharma Services(2)
52,909 43,026 26,382 
Total cost of revenue297,269 258,555 211,994 
Gross profit:
Clinical Services159,812 166,808 175,549 
Pharma Services27,248 19,085 21,287 
Total gross profit187,060 185,893 196,836 
Operating expenses:
General and administrative221,347 143,794 127,993 
Research and development21,873 8,229 8,487 
Sales and marketing62,594 47,862 47,350 
Total operating expenses305,814 199,885 183,830 
(Loss) income from operations(118,754)(13,992)13,006 
Interest expense, net5,082 7,019 3,713 
Other expense (income), net499 (7,906)4,630 
Gain on investment in and loan receivable from non-consolidated affiliate, net(109,260)(3,955)— 
Loss on extinguishment of debt— 1,400 1,018 
Loss on termination of cash flow hedge— 3,506 — 
(Loss) income before taxes(15,075)(14,056)3,645 
Income tax benefit(6,728)(18,228)(4,361)
Net (loss) income$(8,347)$4,172 $8,006 
(1) Clinical Services cost of revenue in 2021 includes $9.2 million of amortization of acquired Inivata developed technology intangible assets and write-offs of $5.3 million for COVID-19 PCR testing inventory.
(2) Pharma Services cost of revenue in 2021 includes $1.2 million of amortization of acquired Inivata developed technology intangible assets.