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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2021
Income Tax Disclosure [Abstract]  
Schedule of Components of Income Tax Expense (Benefit)
(Loss) income before income tax benefit for the years ended December 31, 2021, 2020, and 2019 is as follows (in thousands):
 202120202019
(Loss) income before income tax expense (benefit):
Domestic$24,761 $(6,954)$7,053 
Foreign(39,836)(7,102)(3,408)
Total$(15,075)$(14,056)$3,645 
Income tax expense (benefit)
Current:   
Federal$41 $(434)$(303)
State41 273 290 
Total current tax (benefit) expense$82 $(161)$(13)
Deferred:
Federal$(575)$(12,856)$(3,409)
State1,241 (5,211)(939)
Foreign(7,476)— — 
Total deferred benefit provision$(6,810)$(18,067)$(4,348)
Total tax benefit provision$(6,728)$(18,228)$(4,361)
Schedule of Effective Income Tax Rate Reconciliation
A reconciliation of the differences between the effective tax rate and the federal statutory tax rate for the years ended December 31, 2021, 2020 and 2019 is as follows:
 202120202019
Federal statutory tax rate21.00 %21.00 %21.00 %
State income taxes, net of federal income tax benefit17.77 %14.29 %(19.47)%
Transaction Costs(10.11)%— %— %
Penalties(15.61)%(0.01)%0.08 %
Non-deductible expenses(3.29)%(1.41)%7.41 %
Compensation expense(0.96)%65.78 %(135.12)%
Inivata acquisition fair value adjustment159.14 %— %— %
Tax credits11.63 %32.11 %— %
Uncertain tax position0.22 %1.21 %(3.32)%
Return to provision and other deferred tax adjustments— %7.38 %(13.20)%
Foreign tax rate differential2.74 %(1.64)%— %
Other, net0.16 %(0.06)%(2.78)%
Valuation allowance(138.07)%(8.97)%25.74 %
Effective tax rate44.62 %129.68 %(119.66)%
Schedule of Deferred Tax Assets and Liabilities
At December 31, 2021 and 2020, deferred income tax assets and liabilities consisted of the following (in thousands):
 20212020
Deferred tax assets:
Accounts receivable, net$295 $1,286 
Accrued compensation6,171 5,403 
Net operating loss carry-forwards81,903 33,888 
Tax credits6,596 4,575 
Stock-based compensation2,355 1,999 
Operating lease liabilities19,978 11,589 
Interest expense886 — 
Other2,668 1,470 
     Gross deferred tax assets120,852 60,210 
     Less: valuation allowance(33,014)(2,631)
Total deferred tax assets87,838 57,579 
Deferred tax liabilities:
Operating lease right-of-use assets(19,094)(11,120)
Investment in non-consolidated affiliate— (1,000)
Convertible debt discount(1)(6,636)
Intangible assets (108,592)(29,268)
Property and equipment(15,389)(14,678)
Other— (292)
Total deferred tax liabilities (143,076)(62,994)
Net deferred income tax liabilities$(55,238)$(5,415)
Summary of Positions for which Significant Change in Unrecognized Tax Benefits is Reasonably Possible
20212020
Unrecognized tax benefits - January 1$1,670 $444 
Increases in prior year positions83 1,020 
Reversals of prior year positions— — 
Increases in tax positions taken in current year632 378 
Statute expirations(34)(172)
Unrecognized tax benefits - December 31$2,351 $1,670