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Preferred Shares and Common Shares (Details Narrative) - USD ($)
3 Months Ended
Mar. 06, 2018
Mar. 05, 2018
Feb. 06, 2018
Sep. 20, 2017
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Apr. 10, 2018
Sep. 30, 2017
Sale of stock price, per share               $ 8.51  
Warrant term                 2 years
Warrant exercise price per share                 $ 30.00
Fair value of warrants   $ 2,525,567              
Conversion of preferred stock into common stock, number shares issued   3,045,034              
Number of warrants exchanged to purchase common stock                 322,727
Preferred stock, shares authorized         25,000,000   25,000,000    
Convertible preferred stock, shares outstanding         0   0    
Warrant Liability [Member]                  
Gain/loss on extinguishment of warrant liability           $ 519,467      
6% Series F Convertible Preferred Stock [Member]                  
Preferred stock, stated value per share         $ 2,750        
Preferred stock initial conversion price, per share         $ 27.50        
6% Series F Convertible Preferred Stock [Member] | Accredited Investors [Member]                  
Sales of stock amount       $ 17,750,000          
Sale of stock price, per share       $ 2,750          
Preferred stock, stated value per share       $ 0.001          
Conversion of stock shares converted       100          
Warrant term       2 years          
Warrants to purchase shares of common stock       322,727          
Warrant exercise price per share       $ 30.00          
Series F Preferred Stock [Member]                  
Description on certificate of designation         On the two-year anniversary of the initial issuance date, any Series F Preferred Shares outstanding and not otherwise already converted, would, at the option of the holder, either (i) automatically convert into common stock of the Company at the conversion price then in effect or (ii) be repaid by the Company based on the stated value of such outstanding Series F Preferred Shares.        
Fair value of warrants         $ 4,300,000        
Bifurcated embedded conversion feature         9,300,000        
Preferred stock dividends         $ 13,600,000        
Beneficially ownership percentage 100.00%                
Number of warrants exchanged to purchase common stock 322,727                
Preferred stock reduction in additional paid in capital           $ 698,000      
Series F Preferred Stock [Member] | Restricted Stock [Member]                  
Conversion of stock shares converted 972,070                
Conversion price, per share $ 18.26                
Preferred stock dividend percentage 6.00%                
Conversion of preferred stock into common stock, number shares issued 31,321                
Number of warrants exchanged to purchase common stock 151,871                
Series B Preferred Shares [Member]                  
Conversion of stock shares converted     15,756            
Beneficially ownership percentage 100.00%                
Conversion of preferred stock into common stock, number shares issued 7,945,250   262,606            
Series A Preferred Shares [Member]                  
Beneficially ownership percentage 100.00%                
Conversion of preferred stock into common stock, number shares issued 7,945,250                
Series E Preferred Shares [Member]                  
Beneficially ownership percentage 100.00%                
Series E Preferred Shares [Member]                  
Conversion of preferred stock into common stock, number shares issued 7,945,250                
Series E Preferred Shares [Member] | Lough Registration Rights Agreement [Member]                  
Conversion of preferred stock into common stock, number shares issued 7,050,000