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Loss Per Share (Tables)
3 Months Ended
Mar. 31, 2019
Earnings Per Share [Abstract]  
Schedule of Anti-dilutive Potential Shares Outstanding Activity

The following outstanding potentially dilutive shares have been excluded from the calculation of diluted net loss per share for the periods presented due to their anti-dilutive effect:

 

    For the Three Months Ended March 31  
    2019     2018  
Shares issuable upon exercise of stock options     6,576,816       4,814,568  
Non-vested shares under restricted stock grants     516,875       199,375