Net (Loss) Earnings per Share Applicable to Common Stockholders (Details) - shares shares in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Net (Loss) Earnings per Share Applicable to Common Stockholders
Potentially dilutive securities	477,773	396,039	643,210
Series C convertible preferred stock
Net (Loss) Earnings per Share Applicable to Common Stockholders
Potentially dilutive securities	35,384
Common stock options
Net (Loss) Earnings per Share Applicable to Common Stockholders
Potentially dilutive securities	301,263	266,350	308,840
Common stock warrants
Net (Loss) Earnings per Share Applicable to Common Stockholders
Potentially dilutive securities	141,048	129,689	328,979
Contingently issuable warrants
Net (Loss) Earnings per Share Applicable to Common Stockholders
Potentially dilutive securities			2,774
Convertible notes and accrued interest
Net (Loss) Earnings per Share Applicable to Common Stockholders
Potentially dilutive securities	78		2,617