Related Party Transactions - (Details) shares in Millions		1 Months Ended				3 Months Ended	9 Months Ended
	Sep. 26, 2022 item	Jul. 31, 2022	Apr. 30, 2022 item	Jul. 31, 2021	Jul. 31, 2020	Sep. 30, 2022 USD ($) ft² item	Sep. 30, 2022 USD ($) ft² item Milestone shares	Sep. 30, 2022 GBP (£) Milestone item shares	Sep. 30, 2021 USD ($)	Dec. 31, 2021 USD ($)
Related Party Transactions
Extended term of the Ancillary Services agreement		12 months		12 months			12 months	12 months
Number of required licenses for the Sawston facility | item	3		3
Amount recognized and expensed related to current cash component							$ 1,500,000
Amount recognized and expensed related to cash component							$ 3,800,000
Shares in milestone cost | shares							2.5	2.5
Amount recognized and expensed related to stock component							$ 4,600,000
Number of milestones completed | Milestone							3	3
Lease payments							$ 689,000		$ 603,000
Sub-lease income						$ 37,000	110,000
Capitalized cost							28,000		$ 1,400,000
Accounts payable to related party
Related Party Transactions
Unpaid board compensation						900,000	900,000
Advent BioServices - amount invoiced
Related Party Transactions
Accounts payable and accrued expenses						$ 892,000	$ 892,000			$ 3,046,000
Ancillary Services Agreement
Related Party Transactions
Term (in months)					8 months
Advent BioServices Notes
Related Party Transactions
Number of workstreams | item			5
Advent BioServices - amount accrued
Related Party Transactions
Area of sublease (in sqft) | item						14,459	14,459
Total area of lease (in sqft) | ft²						88,000	88,000
Number of times calculated for lease payment under sub-lease | item							2	2
Rate per square foot under sub-lease							$ 7.76	£ 5.75
Cap rate per square foot under sub-lease							10
Sub-lease payments receivable							144,590
Lease payments | £								£ 500,000
Accounts payable and accrued expenses						$ 4,698,000	4,698,000			$ 3,046,000
Advent Bioscience accrued
Related Party Transactions
Number of workstreams | item	6
Accounts payable and accrued expenses						$ 3,806,000	$ 3,806,000