SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* Woodford Investment Management LLP (Last) (First) (Middle) 9400 GARSINGTON ROAD (Street) OXFORD OX4 2NH X0 00000 (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 11/05/2015	3. Issuer Name and Ticker or Trading Symbol NORTHWEST BIOTHERAPEUTICS INC [ NWBO ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)	5. If Amendment, Date of Original Filed (Month/Day/Year)
			6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common stock, $0.001 par value per share	25,915,937(1)	I	See footnote(2)
Common stock, $0.001 par value per share	18,316,679(3)	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* Woodford Investment Management LLP (Last) (First) (Middle) 9400 GARSINGTON ROAD (Street) OXFORD OX4 2NH X0 00000 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* CF Woodford Equity Income Fund (Last) (First) (Middle) 40 DUKES PLACE, (Street) LONDON, EC3A 7NH X0 00000 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. This statement is being filed jointly by Woodford Investment Management LLP ("WIM") and CF Woodford Equity Income Fund (the "Woodford Fund"). Neil Woodford, the Head of Investments for WIM, by virtue of his position as such, may be deemed to beneficially own the reported securities beneficially owned by WIM. Mr. Woodford expressly disclaims beneficial ownership of the reported securities except to the extent of any pecuniary interest therein.

2. WIM is an investment manager for the investment funds (including but not limited to the Woodford Fund) that own the reported securities.

3. These are shares owned directly by the Woodford Fund and indirectly by WIM. WIM is the Manager of the Woodford Fund, and WIM may be deemed to be the beneficial owner of the reported securities beneficially owned by the Woodford Fund. The Woodford Fund may also be deemed to be the beneficial owner of such reported securities because the Management Agreement between the Woodford Fund and WIM may be terminated at any time upon 60 days' or less notice.

Remarks:

*As Head of Compliance and Authorized Signatory for WIM. **As Head of Compliance and Authorized Signatory for WIM in its capacity as the Manager of the Woodford Fund.

	/s/ Simon Osborne*	11/16/2015
	/s/ Simon Osborne**	11/16/2015
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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