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Share-based Compensation (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 19, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Common stock issued as compensation       $ 127,000 $ 3,389,000
Stock Issued During Period, Shares, Other     80,068    
Cognate Bioservices [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Allocated Share-based Compensation Expense $ 38,800,000     86,000 2,700,000
Common stock issued as compensation       $ 13,600,000 $ 40,800,000
Shares payment due to Cognate BioServices (in Shares)   8,100,000   175,000 318,116
Others [Member]          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Common stock issued as compensation       $ 41,000 $ 700,000
Stock Issued During Period, Shares, Other       75,000 85,228