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Related Party Transactions (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Related Party Transaction [Line Items]        
Cognate research and development cost - services $ 21,094 $ 9,138 $ 43,247 $ 56,562
Cognate Bioservices [Member]        
Related Party Transaction [Line Items]        
Cognate research and development cost - services 6,794 10,137 21,135 29,992
Stock issued to and returned by Cognate 11,376 (6,385) 13,653 9,400
Total $ 18,170 $ 3,752 $ 34,788 $ 39,392