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Balance Sheet Components - Accrued Liabilities (Detail) - USD ($)
$ in Thousands
Dec. 31, 2016
Dec. 31, 2015
Payables And Accruals [Abstract]    
Accrued compensation and benefits $ 14,382 $ 5,722
Accrued consulting and professional fees 9,488 4,508
Accrued research and development services 8,551 8,805
Other 3,608 1,195
Accrued liabilities $ 36,029 $ 20,230